ArticleJournal of fluorescence2025
Dual-Functional Silicon-Based Nanofluorescent Platform for Iron Detection and Capecitabine Delivery in Colorectal Cancer Treatment.
Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Colorectal cancer (CRC) poses significant challenges due to its high incidence and mortality. Addressing limitations like poor bioavailability and off-target effects of traditional chemotherapy, we engineered PDMS-CP1@1@Capecitabine nanoparticles. This novel formulation incorporates a gadolinium-based coordination polymer synthesized via a hydrothermal reaction with a thiourea Schiff-base ligand and embedded in a polydimethylsiloxane (PDMS) matrix, enhanced by the bioactive compound 1 from actinomycetes. Structural characterization demonstrated a crystalline nature with distinct XRD peaks at 21.4° and 25.6°, alongside remarkable fluorescence with peak emission at 444 nm and superior Fe
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.