Evidence map›Paper›PMID 40116954›Full record

Trial reportClinical oral investigations2025

The effects of β-TCP and/or xenogeneic bone substitute on alveolar ridge preservation: a randomized clinical trial.

Liu Gao, Huilin Zhu, Yuqian Kou, Hongcheng Hu, Yuwei Wu, Zhihui Tang, Qing Li

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Liu Gao *Second Clinical Division, Peking University School and Hospital of Stomatology, 22 Zhongguancun Nan Road Haidian District, Beijing, 100081, China.
Huilin Zhu *Second Clinical Division, Peking University School and Hospital of Stomatology, 22 Zhongguancun Nan Road Haidian District, Beijing, 100081, China.
Yuqian KouSecond Clinical Division, Peking University School and Hospital of Stomatology, 22 Zhongguancun Nan Road Haidian District, Beijing, 100081, China.
Hongcheng HuSecond Clinical Division, Peking University School and Hospital of Stomatology, 22 Zhongguancun Nan Road Haidian District, Beijing, 100081, China.
Yuwei WuSecond Clinical Division, Peking University School and Hospital of Stomatology, 22 Zhongguancun Nan Road Haidian District, Beijing, 100081, China.
Zhihui TangSecond Clinical Division, Peking University School and Hospital of Stomatology, 22 Zhongguancun Nan Road Haidian District, Beijing, 100081, China.
Qing LiCenter of Digital Dentistry, Peking University School and Hospital of Stomatology, Beijing, China. lq1996@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAfter tooth extraction, the alveolar ridge undergoes significant absorption, and the alveolar ridge preservation (ARP) will alleviate the complexity of implantation operations in specific clinical occasions and then improve the functionality and aesthetics of subsequent restoration. However, the effectiveness of β-tricalcium phosphate (β-TCP) composite materials for ARP needs to be confirmed by more clinical trials and more sufficient evidence. This study was aimed at evaluating the effects of β-TCP coating porous bovine deproteinization bone (β-TCP/PBDB) on ARP when compared with Bio-Oss MATERIALS AND

methodsAfter baseline clinical examination, teeth extractions and the ARP were conducted randomly by β-TCP/PBDB or the Bio-Oss

resultsIn the clinical trial, a total of 123 patients successfully completed the protocol. The surgical socket and the soft tissues healed well. The reduction of alveolar ridge width was 1.27 ± 1.32 mm, 0.89 ± 1.31 mm, and 0.63 ± 1.37 mm at three levels (1 mm, 3 mm, 5 mm) below the crest of alveolar ridge respectively using β-TCP/PBDB, while those were 1.12 ± 1.65 mm, 0.55 ± 1.41 mm, 0.56 ± 1.32 mm respectively in the Bio-Oss

conclusionsThis prospective, randomized, controlled clinical trial provided evidence that β-TCP/PBDB is a safe material and the effectiveness of β-TCP/PBDB in maintaining the volume and contour of the alveolar ridge is comparable to that of the Bio-Oss CLINICAL RELEVANCE: The β-TCP/PBDB can be used as one option of bone substitute material for ARP.

Indexed as

Alveolar Bone LossAlveolar Ridge AugmentationBone SubstitutesCalcium PhosphatesMineralsAdultAgedAlveolar ProcessAnimalsCattleCone-Beam Computed TomographyFemaleHumansMaleMiddle AgedTooth Extractionbeta-tricalcium phosphateBio-OssBone SubstitutesCalcium PhosphatesMineralsAlveolar ridge preservation (ARP)Bio-Oss®Hydroxyapatite (HA)Β-tricalcium phosphate (β-TCP)

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.