ArticleNeuroradiology2025
Usefulness of 3T split acquisition fast spin-echo diffusion-weighted imaging for differentiating pituitary abscess from other sellar cystic lesions: a preliminary study.
Article in Neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposePituitary abscess is a rare condition that can be challenging to distinguish from other sellar cystic lesions (OSCLs) due to no specific symptoms and overlapping imaging features. Accurate differentiation is crucial for appropriate treatment planning. This study aimed to evaluate the usefulness of 3T split acquisition fast spin-echo diffusion-weighted imaging (SPLICE-DWI) in differentiating pituitary abscesses from OSCLs.
methodsWe retrospectively analyzed magnetic resonance imaging (MRI) data from 32 patients with sellar cystic lesions, including 5 with pathologically confirmed pituitary abscesses and 27 with OSCLs. Conventional MRI sequences and SPLICE-DWI were performed, and apparent diffusion coefficient (ADC) values were calculated. Qualitative assessments of signal intensity on SPLICE-DWI and conventional MRI were conducted by two neuroradiologists. The diagnostic performance of these imaging parameters was evaluated using receiver operating characteristic (ROC) analysis.
resultsSPLICE-DWI successfully differentiated pituitary abscesses from OSCLs, showing significantly lower ADC values in the abscess group compared to OSCLs (0.62 ± 0.07 × 10
conclusionSPLICE-DWI is a valuable tool for the differentiation of pituitary abscesses from OSCLs, offering high diagnostic accuracy.
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