Evidence map›Paper›PMID 40116895›Full record

ArticleAesthetic plastic surgery2025

Helium-Based Plasma Radio Frequency Technology for Subdermal Coagulation in the Forehead: A Preliminary, Single-Center Retrospective Study.

Aris Sterodimas, Beatriz Nicaretta, Agathi Koytsouveli, Argyris Moutafis, Grigoris Champsas

Abstract read
In one paragraph

Article in Aesthetic plastic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aris SterodimasMetropolitan General Hospital, 264 Mesogeion Ave, 15562, Athens, Greece. aris@sterodimas.com.
Beatriz NicarettaVice Head Plastic & Reconstructive Surgery Department, Metropolitan General Hospital, Athens, Greece.
Agathi KoytsouveliMetropolitan General Hospital, 264 Mesogeion Ave, 15562, Athens, Greece.
Argyris MoutafisMetropolitan General Hospital, 264 Mesogeion Ave, 15562, Athens, Greece.
Grigoris ChampsasMetropolitan General Hospital, 264 Mesogeion Ave, 15562, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHelium plasma radio frequency (RF) has emerged as a minimally invasive option for treating facial laxity. This study aims to evaluate its efficacy and safety for addressing forehead and brow laxity and ptosis.

methodsIn this retrospective, single-center study, medical records for 30 consecutive patients treated with helium plasma RF in the forehead and brow from March 2018 to September 2022 were reviewed. Inclusion criteria were age ≥18 years and having undergone treated in the forehead with helium plasma RF. Patients with prior or concurrent brow/forehead interventions were excluded. Primary endpoints were photographic assessments by blinded review and patient satisfaction measured via questionnaire.

resultsOf the 30 patients, seven patients consented to photographic review, and all 30 participated in the patient satisfaction questionnaire. Blinded reviewers correctly identified posttreatment images in 71.4% (5/7) of cases. Patient satisfaction was high, with 100% (30/30) reporting visible improvements and willingness to recommend the procedure. Notable improvements included reduced forehead lines (56.7%), elevated eyebrows (46.7%), and a more youthful appearance (46.7%). Adverse effects were minor and expected, with bruising recorded in 20% (6/30) of patients and edema/swelling in 16.7% (5/30) of patients, all resolving within 10 days, without intervention.

conclusionHelium plasma RF demonstrates significant potential as a minimally invasive treatment for brow and forehead laxity, with high patient satisfaction and a favorable safety profile. These preliminary findings warrant further prospective studies with larger sample sizes to confirm efficacy and long-term benefits. Helium plasma RF may provide a valuable alternative to traditional aesthetic procedures for the forehead and brow. LEVEL OF EVIDENCE IV: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors   www.springer.com/00266 .

Indexed as

ForeheadHeliumAdultAgedEstheticsFemaleHumansMaleMiddle AgedPatient SatisfactionRetrospective StudiesSkin AgingTreatment OutcomeHeliumBrow liftFibroseptal networkForehead liftHelium plasma and radio frequency (RF)RenuvionSkin laxitySubdermal coagulation

Identifiers

PMID40116895
PMCPMC12423226

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.