Evidence map›Paper›PMID 40116781›Full record

Trial reportAmerican journal of respiratory and critical care medicine2025

Telacebec, a Potent Agent in the Fight against Tuberculosis: Findings from a Randomized, Phase 2 Clinical Trial and Beyond.

Saskia Janssen, Caryn Upton, Veronique R de Jager, Christo van Niekerk, Rodney Dawson, Jane Hutchings, Jeongjun Kim, Jinho Choi, Kiyean Nam, Eugene Sun and 1 more

Abstract readRandomized Controlled TrialClinical Trial, Phase II
PubMed Publisher
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Imidazo[1,2‑ACS omega · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Imidazo[1,2‑ACS omega · 2026
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. New drugs for the management of tuberculosis.Current opinion in infectious diseases · 2025
    Review
  11. Review
  12. The role of cytochrome bcNature communications · 2025
    Article
  13. A Telacebec-Shaped Puzzle Piece in the Treatment of Mycobacterial Diseases.American journal of respiratory and critical care medicine · 2025
    Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Saskia JanssenTASK, Cape Town, South Africa.ORCID 0000-0003-0966-3233
Caryn UptonTASK, Cape Town, South Africa.
Veronique R de JagerTASK, Cape Town, South Africa.
Christo van NiekerkQurient Co. Ltd., Seongnam, South Korea.
Rodney DawsonUniversity of Cape Town Lung Institute, Cape Town, South Africa; and.
Jane HutchingsQurient Co. Ltd., Seongnam, South Korea.
Jeongjun KimQurient Co. Ltd., Seongnam, South Korea.
Jinho ChoiQurient Co. Ltd., Seongnam, South Korea.
Kiyean NamQurient Co. Ltd., Seongnam, South Korea.
Eugene SunTB Alliance, New York, New York.
Andreas H DiaconTASK, Cape Town, South Africa.ORCID 0000-0001-8641-6792

Funding

Horizon Europe Framework Programme HORIZON-MSCA-2021-PF-GF, number 101063247
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antitubercular AgentsTuberculosis, PulmonaryAdultAgedDose-Response Relationship, DrugFemaleHumansMaleMiddle AgedMycobacterium tuberculosisSputumTreatment OutcomeAntitubercular AgentsBuruli ulcerleprosytreatmenttuberculosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.