Evidence map›Paper›PMID 40116492›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2025

Unlocking Multimodal Nonlinear Microscopy for Deep-Tissue Imaging under Continuous-Wave Excitation with Tunable Upconverting Nanoparticles.

Jeongmo Kim, Seunghun Lee, Yundon Jeong, Kyunghwan Kim, Kibum Nam, Hyungwon Jin, Yuha Choi, Hyun-Jin Kim, Heungjin Ryu, Ki Hean Kim and 4 more

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jeongmo KimDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Seunghun LeeDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Yundon JeongDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Kyunghwan KimDepartment of Chemistry, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Kibum NamDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Hyungwon JinDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Yuha ChoiDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Hyun-Jin KimDepartment of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Heungjin RyuDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Ki Hean KimDivision of Integrative Biosciences and Biotechnology, Pohang University of Science and Technology, 77 Cheongam-Ro, Nam-gu, Pohang, Gyeongbuk, 37673, Republic of Korea.
Jae-Ick KimDepartment of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Jongnam ParkDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.
Jinmyoung JooDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.ORCID https://orcid.org/0000-0003-1574-9842
Jung-Hoon ParkDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.

Funding

Korea Basic Science Institute RS-2024-00403508Korean Fund for Regenerative Medicine 22A0102L1-11Ministry of Health and Welfare RS-2020-KH106391Ministry of Science and ICT, South Korea IITP-2023-RS-2023-00259676National Research Foundation of Korea 2019M3E5D2A01063812National Research Foundation of Korea 2021R1A2C3012903National Research Foundation of Korea 2021R1A4A1031644National Research Foundation of Korea RS-2023-00264980National Science Foundation DMR-2011924POSCO TJ Park Foundation
6 · The paper itself

Abstract

Nonlinear microscopy provides excellent depth penetration and axial sectioning for 3D imaging, yet widespread adoption is limited by reliance on expensive ultrafast pulsed lasers. This work circumvents such limitations by employing rare-earth doped upconverting nanoparticles (UCNPs), specifically Yb

Indexed as

MicroscopyNanoparticlesAnimalsBrainCerebrovascular CirculationImaging, Three-DimensionalMiceNonlinear Dynamicscontinuous‐wave excitationdeep‐tissue imagingmultimodal imagingnonlinear microscopyupconverting nanoparticle

Identifiers

PMID40116492
PMCPMC12075917

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.