Evidence map›Paper›PMID 40116373›Full record

ArticleEnvironmental science & technology2025

Organophosphorus Flame Retardant, Phthalate, and Alternative Plasticizer Contamination in Novel Plant-Based Food: A Food Safety Investigation.

Alicia Macan Schönleben, Fatima den Ouden, Shanshan Yin, Erik Fransen, Stijn Bosschaerts, Mirjana Andjelkovic, Nayyer Rehman, Alexander L N van Nuijs, Adrian Covaci, Giulia Poma

Abstract read
In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alicia Macan SchönlebenToxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.
Fatima den OudenToxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID 0000-0001-6862-6059
Shanshan YinToxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.
Erik FransenCentre of Medical Genetics, University of Antwerp and Antwerp University Hospital, 2650 Edegem, Belgium.
Stijn BosschaertsToxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.
Mirjana AndjelkovicSciensano, Service Risk and Health Impact Assessment, Juliette Wytsmanstraat 14, 1050 Brussels, Belgium.
Nayyer RehmanWRG Europe Ltd., 26-28 Southernhay East, EX1 1NS, Exeter, U.K.
Alexander L N van NuijsToxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID 0000-0002-9377-6160
Adrian CovaciToxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID 0000-0003-0527-1136
Giulia PomaToxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.ORCID 0000-0003-0597-2653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With plant-based (PB) diets gaining popularity, ultraprocessed novel plant-based foods (NPBFs) are an increasingly available alternative to animal-based foods (ABFs). The degree of industrial food processing has been associated with higher organophosphorus flame retardant (PFR) and plasticizer contamination. Here, the occurrence of these contaminants in NPBFs was investigated by using liquid chromatography-tandem mass spectrometry. Our findings show differences in contamination levels and patterns between PB food categories, with PB cheese-alternatives showing the highest levels of both total PFRs (mean: 123 ng/g ww) and total plasticizers (mean: 1155 ng/g ww). The results further point to food contact material and industrial processing as possible contamination sources. Compared with previous studies of ABFs, NPBFs generally showed higher contamination levels, leading to a higher dietary exposure in a vegan diet scenario. While the adult population is not at immediate risk following NPBF consumption, based on these results, a direct replacement of all ABFs with NPBFs is not recommended. Additionally, it is suggested that different PB food categories be included in future food studies monitoring dietary exposure.

Indexed as

Flame RetardantsFood ContaminationFood SafetyPlasticizersOrganophosphorus CompoundsPhthalic AcidsFlame RetardantsOrganophosphorus CompoundsPhthalic AcidsPlasticizersAlternative ProteinsEmerging contaminantsExposomeHuman exposureRisk assessmentVegan diet

Identifiers

PMID40116373
PMCPMC12080256

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.