Evidence map›Paper›PMID 40116295›Full record

ArticleCancer medicine2025

An Ecological Analysis of HPV Vaccination in the United States Before and During the COVID-19 Pandemic by Age, Sex, and Urbanicity Using Private Insurance Claims Data.

Milkie Vu, Jingjing Li, Kai Hong, Jennifer W Kaminski, Bo-Hyun Cho, Yoonjae Kang

Abstract read
In one paragraph

Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Milkie VuDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0003-0230-473X
Jingjing LiDepartment of Behavior, Social, and Health Education Sciences, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Kai HongOffice of Policy, Performance, and Evaluation, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jennifer W KaminskiOffice of Policy, Performance, and Evaluation, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Bo-Hyun ChoThe National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Yoonjae KangThe National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)KL2TR001424 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHARMA, LEENA · 2015 to 2023
$8.1M
Cancer Prevention, Control, and Survivorship Research Training ProgramT32CA193193 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Brian L Hitsman, BETINA YANEZ · 2015 to 2026
$3.8M
NUCATS CTSA K12 Program at Northwestern UniversityK12TR005104 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Leena Sharma, BETINA YANEZ · 2024 to 2026
$3.2M
Applying the Multiphase Optimization Strategy to Develop and Test a Digital Health Intervention Targeting HPV PreventionK01CA296781 · NCI · NORTHWESTERN UNIVERSITY · PI Ha Ngan Vu · 2025 to 2026
$383k
NCATS NIH HHS K12 TR005104NCATS NIH HHS K12TR005104NCATS NIH HHS KL2 TR001424NCATS NIH HHS KL2TR001424NCI NIH HHS K01 CA296781NCI NIH HHS K01CA296781NCI NIH HHS T32 CA193193NCI NIH HHS T32CA193193
6 · The paper itself

Abstract

introductionWe aim to assess HPV vaccine administration among privately insured populations before and during the COVID-19 pandemic in the United States and stratify the assessments by demographic and geographic characteristics.

methodsUsing the Merative MarketScan Commercial Claims and Encounters Database, we estimated monthly and yearly HPV vaccine administration among people aged 9-26 from 2019 to 2022, measured as the proportion of the enrolled population who received ≥ 1 dose of HPV vaccine during that month or year, and their relative percent change from 2020 to 2022, compared to the same period in 2019, overall and stratified by age group, sex, and urbanicity.

resultsHPV vaccine administration in 2020, 2021, and 2022 was lower than in 2019 and continued to decline for all age groups. The relative percent change in rate in 2022 relative to 2019 was -6.0% among children, -38.3% among adolescents, and -42.5% among young adults. The patterns were similar across subgroups, with certain disparities in magnitude. By subpopulations, the highest percent declines in 2022 relative to 2019 in each age group were observed among children in rural areas (-13.5%), male adolescents (-39.8%), and young adults in rural areas (-46.0%).

conclusionDuring the COVID-19 pandemic, HPV vaccine administration dropped substantially and had not exceeded the pre-pandemic levels by the end of 2022, with larger declines seen among male adolescents and young adults in rural areas. Our results highlight the need for continuing monitoring and targeted intervention strategies to improve HPV vaccine administration.

Indexed as

COVID-19Papillomavirus InfectionsPapillomavirus VaccinesVaccinationAdolescentAdultAge FactorsChildFemaleHumansInsurance Claim ReviewInsurance, HealthMalePandemicsSARS-CoV-2Sex FactorsPapillomavirus Vaccines

Identifiers

PMID40116295
PMCPMC11926641

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.