Evidence map›Paper›PMID 40116124›Full record

ArticleMolecular medicine reports2025

Water extract of

Ju-Eun Kim, Kyeong-Seon Min, Jun Go, Hye-Yeon Park, Young-Keun Choi, In-Bok Lee, Jaewon Shin, Hyun-Ju Cho, Hong-Sik Kim, Dae Youn Hwang and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Plants, Pills, and the Brain: Exploring Phytochemicals and Neurological Medicines.International journal of plant, animal and environmental sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ju-Eun Kim *Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Kyeong-Seon Min *Laboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Jun GoLaboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Hye-Yeon ParkLaboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Young-Keun ChoiLaboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
In-Bok LeeLaboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Jaewon ShinKorea Bioactive Natural Material Bank, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Hyun-Ju ChoNHB Co., Ltd., Seoul 04735, Republic of Korea.
Hong-Sik KimPENS Co., Ltd., Seoul 07206, Republic of Korea.
Dae Youn HwangDepartment of Biomaterials Science, College of Natural Resources and Life Science/Life and Industry Convergence Research Institute, Pusan National University, Miryang, South Gyeongsang 50463, Republic of Korea.
Won-Keun OhKorea Bioactive Natural Material Bank, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
Kyoung-Shim KimLaboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
Chul-Ho LeeLaboratory Animal Resource Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aging process is associated with a decline in certain cognitive abilities, including learning and memory. This age‑related cognitive decline is associated with a reduction in neurogenesis and alterations in the cholinergic system.

Indexed as

AcetylcholineAcetylcholinesteraseAgingCholinesterase InhibitorsCognitive DysfunctionPlant ExtractsSignal TransductionAnimalsCyclic AMP Response Element-Binding ProteinDisease Models, AnimalGlycogen Synthase Kinase 3 betaHippocampusMaleMaze LearningMiceNeurogenesisAcetylcholineAcetylcholinesteraseCholinesterase InhibitorsCyclic AMP Response Element-Binding ProteinGlycogen Synthase Kinase 3 betaPlant ExtractsProto-Oncogene Proteins c-aktScopolamineWateracetylcholineagingcognitive functionHumulus japonicusscopolamine‑induced model

Identifiers

PMID40116124
PMCPMC11938412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.