Evidence map›Paper›PMID 40115981›Full record

ArticleJournal of chemical information and modeling2025

Integrative Computational Analysis of Common EXO5 Haplotypes: Impact on Protein Dynamics, Genome Stability, and Cancer Progression.

Fabio Mazza, Davide Dalfovo, Alessio Bartocci, Gianluca Lattanzi, Alessandro Romanel

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fabio MazzaDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, Trento 38123, Italy.ORCID 0009-0005-1611-0487
Davide DalfovoDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, Trento 38123, Italy.
Alessio BartocciDepartment of Physics, University of Trento, Via Sommarive 9, Trento 38123, Italy.ORCID 0000-0001-9413-0663
Gianluca LattanziDepartment of Physics, University of Trento, Via Sommarive 9, Trento 38123, Italy.ORCID 0000-0002-0808-6457
Alessandro RomanelDepartment of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Via Sommarive 9, Trento 38123, Italy.ORCID 0000-0003-4855-8620

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the impact of common germline variants on protein structure, function, and disease progression is crucial in cancer research. This study presents a comprehensive analysis of the

Indexed as

Computational BiologyDisease ProgressionDNA Repair EnzymesExodeoxyribonucleasesGenomic InstabilityHaplotypesMolecular Dynamics SimulationNeoplasmsHumansProtein ConformationDNA Repair EnzymesExodeoxyribonucleases

Identifiers

PMID40115981
PMCPMC12004521

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.