ArticleFrontiers in medicine2025
Association between life's crucial 9 and kidney stones: a population-based study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Mediation of Systemic Inflammation and Oxidative Stress Markers in the Association of Life's Crucial 9 with Periodontitis: Evidence from NHANES 2009-2014.Oral health & preventive dentistry · 2026Article
- The association between life's crucial 9 and osteoarthritis in US adults: the mediating role of central adiposity.Nutrition & metabolism · 2026Article
- Central adiposity indices and inflammatory markers mediate the association between life's crucial 9 and periodontitis in US adults.Lipids in health and disease · 2025Article
- Life's Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening.International journal of chronic obstructive pulmonary disease · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
Purpose: This study examined the association between the Life's Crucial 9 (LC9) score and kidney stone prevalence in U.S. adults. Methods: Using data from the National Health and Nutrition Examination Survey (NHANES) spanning 2007 to 2014, this cross-sectional analysis focused on adult participants with kidney stone onset or recurrence. LC9 scores were divided into four quartiles for analysis. Weighted multivariable logistic regression, restricted cubic spline (RCS) modeling, threshold effect analysis, and subgroup analyses were employed to evaluate the relationship between LC9 scores and kidney stone prevalence. Results: The study included 24,669 participants with an average age of 46.05 ± 0.34 years and a mean LC9 score of 73.76 ± 0.25. The overall prevalence of kidney stones was 8.45%, while the average recurrence rate stood at 2.96%. Importantly, for each one-point increase in the LC9 score, the incidence of kidney stones dropped by 1.2% (95% CI: 0.979 to 0.997, Conclusion: An elevated LC9 score correlates with a lower risk of both kidney stone formation and recurrence. Maintaining an optimal LC9 score could be an effective approach for preventing kidney stones.
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