Evidence map›Paper›PMID 40115574›Full record

ArticleJournal of family medicine and primary care2025

Assessment of nerve conduction studies in insulin-dependent diabetes in children and adolescents at the tertiary care center in eastern Nepal.

Shital Gupta, Rita Khadka, Priza Subedi, Nirmala Limbu, Jyoti Agrawal, Dilip Thakur

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Article in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Shital GuptaDepartment of Basic and Clinical Physiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Rita KhadkaDepartment of Basic and Clinical Physiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Priza SubediDepartment of Basic and Clinical Physiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Nirmala LimbuDepartment of Basic and Clinical Physiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.
Jyoti AgrawalP.T. Birta City Hospital and Research Centre, Birtamod, Jhapa, Nepal.
Dilip ThakurDepartment of Basic and Clinical Physiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Young adults suffering from Type 1 Diabetes mellitus may have diabetic peripheral neuropathy without any signs and symptoms, as one of the complications. Nerve conduction study is routinely used for evaluation of neuromuscular function. This study aimed to conduct a nerve conduction study in insulin-dependent type 1 diabetes mellitus in children and adolescents. Methods: It was a cross-sectional, descriptive study conducted on 16 diagnosed cases of diabetes mellitus in children aged between 5-15 years and 16 healthy controls. Children were selected based on inclusion criteria from Pediatric and adolescent diabetic clinics who came for follow-up. A motor nerve conduction study of the median, tibial, and common peroneal nerves was recorded, and a sensory nerve conduction study of the median and sural nerves was recorded. Results: The percentage of females was 46.4% and males were 53.6%. The age of diabetic children was (mean ± SD) 9.75 ± 3.53 and healthy control was 10.75 ± 3.14. A comparison of sensory nerve conduction parameters between type one diabetes in children and healthy control; onset latency of the sural nerve was prolonged on the bilateral side in diabetes children. Similarly, the SNAP amplitude of the median and sural nerves was decreased in diabetes children. Conclusions: In type 1 diabetes in children, peripheral nerves get affected even in asymptomatic patients in children. More disease duration and uncontrolled glucose levels will lead to the involvement of nerves getting affected. Proper follow-up is needed for better management.

Indexed as

Children and adolescentsperipheral neuropathytype 1 diabetes mellitus

Identifiers

PMID40115574
PMCPMC11922370

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