Evidence map›Paper›PMID 40115552›Full record

ArticleJournal of family medicine and primary care2025

Determining correlation between changes in blood pressure and vitamin D levels: Analyzing influencing factors in hypertensive adults at Family Medicine Clinics.

Aayesha Butt, Swaleha Tariq, Fatima Kanwal

Abstract read
In one paragraph

Article in Journal of family medicine and primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Aayesha ButtDepartment Family Medicine, Dow University of Health Sciences, Karachi, Sindh, Pakistan.
Swaleha TariqDepartment Family Medicine, Aga Khan University Hospital, Karachi, Sindh, Pakistan.
Fatima KanwalDepartment Family Medicine, Dow University of Health Sciences, Karachi, Sindh, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dietary sodium and renin-angiotensin system activity are pivotal in causing primary hypertension. Vitamin D levels inversely relate to the renin-angiotensin system. Our study investigates the association between vitamin D fluctuations and blood pressure control in hypertensive patients undergoing general health checkups. Methodology: A cross-sectional study enrolled participants with essential hypertension from family medicine clinics at the Aga Khan University Hospital, Karachi, coming for a general health checkup. Data including demographics, Vitamin D levels, blood pressure, factors associated with hypertension, and vitamin D deficiency were noted and analyzed using SPSS 20. Post-stratification chi-square test was applied to check for the association between different categorical variables. Results: In a study of 203 hypertensive subjects (mean age: 58.07 ± 11 years, 56.2% male, 63.5% Urdu speaking), 41.4% were smokers, and 63.1% had other comorbidities along with hypertension. Significant vitamin D deficiency was observed in 81.8%, with 55.7% exhibiting uncontrolled blood pressure. Vitamin D levels were significantly associated with blood pressure changes, sun exposure, gender, physical activity, and salt restriction. Smoking and obesity are also correlated with blood pressure changes. Conclusion: Pakistan faces significant hypertension and vitamin D deficiency burdens. Our study found a potential link between varying vitamin D levels and blood pressure fluctuations in hypertensive patients, warranting further research.

Indexed as

25 (OH) Dcalcifediolcholecalciferolhigh blood pressurehypertensionvitamin D

Identifiers

PMID40115552
PMCPMC11922343

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