Evidence map›Paper›PMID 40115494›Full record

ArticleACS applied nano materials2022

Near-Infrared-Triggered Reversible Transformations of Gold Nanorod-Laden Lipid Assemblies: Implications for Cellular Delivery.

Jacob Rueben, Ashish Jayaraman, Mahesh K Mahanthappa, Cecilia Leal

Abstract read
In one paragraph

Article in ACS applied nano materials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Lipid nanoparticle topology regulates endosomal escape and delivery of RNA to the cytoplasm.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jacob RuebenDepartment of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0001-8140-0054
Ashish JayaramanDepartment of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0001-7071-7419
Mahesh K MahanthappaDepartment of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota 55455, United States.ORCID 0000-0002-9871-804X
Cecilia LealDepartment of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID 0000-0001-5972-508X

Funding

A New Paradigm in Nanomedicine: can structural interiors of nanoparticles regulate cellular delivery?DP2EB024377 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI LEAL, CECILIA MARIA · 2016 to 2016
$2.3M
NIBIB NIH HHS DP2 EB024377
6 · The paper itself

Abstract

Robust drug and gene delivery systems require innovative methods to control payload release and tune delivery efficiency. The most promising delivery materials are lipid-based and their efficiency often hinges on structural transformations activated by endogenous pH changes. Exogenously driving phase transitions in lipid assemblies is a tantalizing idea that could lead to better control of cargo release dynamics. Multiple reports have demonstrated phase transitions induced in lipid systems, achieved

Indexed as

electron reconstructiongold nanorodslipidsnonlamellarphase activationremote triggering

Identifiers

PMID40115494
PMCPMC11922641

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.