Evidence map›Paper›PMID 40115309›Full record

ArticleRevista Cuidarte

Non-pharmacological interventions for side effects of antineoplastic chemotherapy prioritized by patients: systematic review.

María Elizabeth Gómez-Neva, Edwin Pulido-Ramirez, Leidy Johana Ibañez-Rodriguez, Oscar Caroprese, Adriana Buitrago-Lopez

Abstract read
In one paragraph

Article in Revista Cuidarte. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

María Elizabeth Gómez-NevaPontificia Universidad Javeriana, Facultad de Enfermería. Bogotá, Colombia. E-mail: m.gomezn@javeriana.edu.co Pontificia Universidad Javeriana Pontificia Universidad Javeriana Facultad de Enfermería Bogotá Colombia m.gomezn@javeriana.edu.co.
Edwin Pulido-RamirezPontificia Universidad Javeriana. Departamento de Epidemiología Clínica y Bioestadística, Facultad de Medicina. Bogotá, Colombia. E-mail: pulidoedwin@javeriana.edu.co Pontificia Universidad Javeriana Pontificia Universidad Javeriana Departamento de Epidemiología Clínica y Bioestadística Facultad de Medicina Bogotá Colombia pulidoedwin@javeriana.edu.co.
Leidy Johana Ibañez-RodriguezHospital Universitario San Ignacio. Bogotá, Colombia. E-mail: leidy.ibanez@javeriana.edu.co Hospital Universitario San Ignacio Bogotá Colombia leidy.ibanez@javeriana.edu.co.
Oscar CaropreseSubred Integrada de Servicios de Salud Norte. Bogotá, Colombia. E-mail: ocaropresse@g mail.com Subred Integrada de Servicios de Salud Norte Bogotá Colombia ocaropresse@g mail.com.
Adriana Buitrago-LopezPontificia Universidad Javeriana, Departamento de Epidemiología Clínica y Bioestadística, Facultad de Medicina. Bogotá, Colombia. E-mail: buitragod@javeriana.edu.co Pontificia Universidad Javeriana Pontificia Universidad Javeriana Departamento de Epidemiología Clínica y Bioestadística Facultad de Medicina Bogotá Colombia buitragod@javeriana.edu.co.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Different non-pharmacological interventions have been studied to manage symptoms derived from chemotherapy, but their effectiveness is unknown. Objective: To describe non-pharmacological interventions for managing symptoms secondary to antineoplastic chemotherapy in adults. Materials and Methods: Systematic review of analytical experimental and observational studies (2021 to 2023). The studies were selected, and data was extracted in parallel. Discrepancies were resolved with a third reviewer. The risk of bias was assessed using the Risk of Bias (RoB) tool and The Newcastle-Ottawa Scale (NOS). The literature was synthesized descriptively based on prioritized outcomes. Results: The prioritized outcomes were neutropenia, pain, neuropathy, nausea, vomiting, alopecia, anorexia, and sleep disorders. Out of 7520 references found, 62 were included for analysis. Acupressure showed a possible effect in controlling symptoms such as nausea and vomiting. The intervention with cold on the scalp showed differences in the stages of alopecia severity. Other interventions showed heterogeneity. Discussion: Non-pharmacological interventions have been widely described in observational and experimental studies in the control of side effects of chemotherapy; however, there is homogeneity and a high risk of bias. Conclusion: Acupressure, muscle massage, music therapy, foot baths, and other interventions have been studied for nausea, vomiting, sleep disorders, neutropenia, alopecia, anorexia, pain, and neuropathy as secondary symptoms prioritized by patients. It is necessary to standardize both the interventions and how measure the outcomes.

Indexed as

Complementary TherapiesDrug-Related Side Effects and Adverse ReactionsIntegrative OncologySigns and Symptoms

Identifiers

PMID40115309
PMCPMC11922587

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.