Evidence map›Paper›PMID 40115243›Full record

ArticleACS agricultural science & technology2025

From Hemp to CBD Crystals: A Scaled-Up Procedure for the Selective Extraction, Isolation, and Purification of Cannabidiol.

Roberto Calmanti, Maurizio Selva, Alvise Perosa

Abstract read
In one paragraph

Article in ACS agricultural science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Roberto CalmantiDipartimento di Scienze Molecolari e Nanosistemi, Università Ca' Foscari Venezia, Via Torino 155, Venezia 30172, Mestre, Italy.ORCID https://orcid.org/0000-0003-1707-1932
Maurizio SelvaDipartimento di Scienze Molecolari e Nanosistemi, Università Ca' Foscari Venezia, Via Torino 155, Venezia 30172, Mestre, Italy.ORCID https://orcid.org/0000-0002-9986-2393
Alvise PerosaDipartimento di Scienze Molecolari e Nanosistemi, Università Ca' Foscari Venezia, Via Torino 155, Venezia 30172, Mestre, Italy.ORCID https://orcid.org/0000-0003-4544-8709

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The isolation of cannabidiol (CBD) with a purity greater than 99%, while avoiding the presence of Δ9-tetrahydrocannabinol (THC), is essential for both exploring CBD applications and its commercialization. The scientific literature lacks robust and scalable protocols for obtaining pure CBD, instead primarily focusing on obtaining hemp extracts with higher cannabinoid content. Herein, we present a complete procedure for obtaining pure CBD crystals, starting from an industrial hemp cultivar. The protocol includes thermal decarboxylation of cannabinoids, supercritical CO

Identifiers

PMID40115243
PMCPMC11921148

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.