Evidence map›Paper›PMID 40115116›Full record

SynthesisFrontiers in physiology2025

Meta-analysis of high-intensity interval training effects on cognitive function in older adults and cognitively impaired patients.

Wenting Zhang, Shuyi Zeng, Yao Nie, Keke Xu, Qiyuan Zhang, Yu Qiu, Yongqiang Li

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenting Zhang *School of Sport and Health Sciences, Nanjing Sport Institute, Nanjing, Jiangsu, China.
Shuyi Zeng *School of Sport and Health Sciences, Nanjing Sport Institute, Nanjing, Jiangsu, China.
Yao NieSchool of Sport and Health Sciences, Nanjing Sport Institute, Nanjing, Jiangsu, China.
Keke XuRehabilitation Medicine Center, Jiangsu Zhongshan Geriatric Rehabilitation Hospital, Nanjing, Jiangsu, China.
Qiyuan ZhangRehabilitation Medicine College, Nanjing Medical University, Nanjing, Jiangsu, China.
Yu QiuSchool of Sport and Health Sciences, Nanjing Sport Institute, Nanjing, Jiangsu, China.
Yongqiang LiRehabilitation Medicine Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cognitive enhancement treatments are limited, and while High-Intensity Interval Training (HIIT) has been suggested to improve cognitive function, high-quality evidence remains scarce. This meta-analysis evaluates the effects of HIIT on cognitive performance compared to moderate-intensity continuous training (MICT) and control groups in older adults and cognitively Impaired Patients. Methods: A systematic search of PubMed, Embase, and Cochrane Library databases was conducted for articles published until 10 October 2024. Eighteen studies were included, comparing cognitive outcomes across HIIT, MICT, and control groups. Cognitive tests evaluated included the Stroop test, Digit Span Test (DST), Trail Making Test (TMT), and the MOST test. Results: HIIT significantly improved performance compared to MICT in the Stroop test (SMD = -0.8, 95% CI: -1.3 to -0.2) and DST (SMD = 0.3, 95% CI: -0.0-0.5). Compared to control groups, HIIT significantly enhanced performance in the TMT (SMD = -0.7, 95% CI: -1.3 to 0.0) and MOST test (SMD = -1.2, 95% CI: -1.8 to -0.7). Conclusion: This meta-analysis supports the efficacy of HIIT in enhancing cognitive functions, particularly in cognitive flexibility, working memory, task switching, attention control, and inhibitory control. These findings suggest that HIIT can be an effective intervention for improving cognitive behavior in older adults and cognitively Impaired Patients. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/, Identifier CRD42023413879.

Indexed as

attentioncognitive flexibilitycognitive functionexercisehigh-intensity interval trainingmoderateintensity continuous training

Identifiers

PMID40115116
PMCPMC11922960

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.