Evidence map›Paper›PMID 40115066›Full record

ArticleAnnals of translational medicine2025

Multimodal anesthesia for hemicorporectomy suggests creating a standardized anesthesia guideline: a case report.

Kelsey M Repine, Tobias de la Garza Eckle, Julio Montejano, Scott Vogel

Abstract readCase Reports
In one paragraph

Article in Annals of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Kelsey M RepineDepartment of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Tobias de la Garza EckleDepartment of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-6065-4669
Julio MontejanoDepartment of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Scott VogelDepartment of Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Funding

Intense Light Therapy for Perioperative Cardio-ProtectionR01HL122472 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI DE LA GARZA ECKLE, TOBIAS · 2015 to 2019
$1.9M
Targeting the endothelial clock to treat perioperative myocardial ischemiaR56HL156955 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI DE LA GARZA ECKLE, TOBIAS · 2022 to 2022
$383k
NHLBI NIH HHS R01 HL122472NHLBI NIH HHS R56 HL156955
6 · The paper itself

Abstract

Background: First performed in 1960, hemicorporectomy, or translumbar amputation, is a rare surgery performed as a last resort for patients with life-threatening diagnoses. While rare, it is associated with significant challenging events for the anesthesiologist. Here we present a challenging hemicorporectomy case which was successfully managed using a multimodal anesthesia approach. Case Description: The patient was a 40-year-old patient presenting for completion of a hemicorporectomy via a left hemipelvectomy for pelvic chondrosarcoma. The patient underwent hemicorporectomy under epidural and total intravenous anesthesia supplemented with ketamine and lidocaine infusion. The surgery lasted 17.5 h and resulted in 28 L of blood loss. The patient noted excellent pain control and was discharged on postoperative day 74 following an uncomplicated hospital course and in-house rehabilitation. Conclusions: Reviewing the literature, we recognized that there are no standardized anesthesia protocols published for hemicorporectomy. Based on our case report we present a novel anesthesia strategy that addresses almost all major challenges with hemicorporectomies. Our successful strategy suggests that a total intravenous anesthesia with propofol in combination with an epidural and a multimodal pain regimen with rate adjustments based on body mass reduction should be considered as a standard anesthesia protocol for hemicorporectomies. We recommend establishing a state-of-the-art anesthesia guideline for patients undergoing hemicorporectomy and encourage anesthesiologists to publish case reports describing the anesthesia approach for a hemicorporectomy.

Indexed as

anesthesiacase reportguidelineHemicorporectomymultimodal

Identifiers

PMID40115066
PMCPMC11921205

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.