ArticlePlastic and reconstructive surgery. Global open2025
A Comparison of Treatment With Skin Graft or Secondary Healing for Nasal Wound Defects After Tumor Excision: A Randomized Study.
Article in Plastic and reconstructive surgery. Global open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Secondary Intention Healing for Facial Skin and Soft Tissue Defects: Case Report and Review of Literature.Aesthetic plastic surgery · 2026Pooled it
- Mohs Surgery vs. Wide Local Excision for Non-Melanoma Skin Cancer: Comparing Recurrence Rates, Economic Value, and Aesthetic Outcomes.Journal of cancer science and clinical therapeutics · 2026Article
- Secondary Intention Healing of Extensive Nasal Defects: A Multimodal Approach to Optimize Esthetic Outcomes.Case reports in dermatological medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: A full-thickness skin graft is a commonly used method for repairing smaller nasal defects. Secondary healing is a simple alternative with many advantages, although it is associated with a long duration of healing. The aim was to compare the short- and long-term results of skin graft transplantation or secondary healing for small nasal wound defects after tumor excision. Methods: Adult patients admitted for nasal tumor resection were randomized to treatment with either full-thickness skin graft or secondary healing intent. Healing and complications were assessed at 1 and 4 weeks. Scar quality was assessed with the patient and observer scar assessment scale (POSAS) 6 months postoperatively. Results: Twenty-six patients were included. Three patients healed within a week in the skin graft group, whereas none had healed after a week in the secondary healing group (SHG). Healing time (median [interquartile range]) was 35.0 (28.0-41.0) days and 28.0 (12.0-48.0) days in the SHG and skin graft group, respectively ( Conclusions: Healing time did not differ between the 2 groups. The cosmetic outcome showed promising results in the SHG, suggesting that allowing secondary healing for superficial, smaller nasal defects after tumor surgery may be beneficial. However, the strength of this conclusion is hampered by the small study group.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.