Evidence map›Paper›PMID 40115011›Full record

ArticleFrontiers in oncology2025

Associations of ANGPT2 expression and its variants (rs1868554 and rs7825407) with multiple myeloma risk and outcome.

Sylwia Popek-Marciniec, Wojciech Styk, Sylwia Chocholska, Aneta Szudy-Szczyrek, Katarzyna Sidor, Grazyna Swiderska-Kolacz, Marek Hus, Joanna Czerwik-Marcinkowska, Szymon Zmorzynski

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Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sylwia Popek-MarciniecLaboratory of Genetics, Academy of Zamosc, Zamosc, Poland.
Wojciech StykAcademic Laboratory of Psychological Tests, Medical University, Lublin, Poland.
Sylwia ChocholskaChair and Department of Hematooncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Poland.
Aneta Szudy-SzczyrekChair and Department of Hematooncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Poland.
Katarzyna SidorAcademic Laboratory of Psychological Tests, Medical University, Lublin, Poland.
Grazyna Swiderska-KolaczInstitute of Biology, Jan Kochanowski University, Kielce, Poland.
Marek HusChair and Department of Hematooncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Poland.
Joanna Czerwik-MarcinkowskaInstitute of Biology, Jan Kochanowski University, Kielce, Poland.
Szymon ZmorzynskiLaboratory of Genetics, Academy of Zamosc, Zamosc, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growth of blood vessels from the existing vasculature has a significant impact on the course of multiple myeloma (MM). The ANGPT2 (angiopoietin-2) protein is encoded by the Purpose: Therefore, we assessed the impact of selected variants on Patients and methods: Genomic DNA extracted from 103 newly diagnosed MM patients and 120 healthy blood donors was used to analyze Results: The results of our study showed that individuals with the AA genotype of rs1868554 and the CC genotype of rs7825407 had a greater risk of developing MM (OR=6.12, p=0.02 and OR=6.01, p=0.02, respectively). The Conclusion: Our results showed that

Indexed as

angiogenesisbortezomibhematology malignanciesplasma cellpolymorphismsthalidomide

Identifiers

PMID40115011
PMCPMC11922703

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