Evidence map›Paper›PMID 40114912›Full record

ArticleIJID regions2025

Blood culture time to positivity in pediatric patients with bloodstream infection in rural Gambia.

Isaac Osei, Baleng Mahama Wutor, Alieu Kuyateh, Ousman Barjo, Golam Sarwar, Mayowa Omotosho, Williams Oluwatosin Adefila, Yusuf Abdulsalam Olawale, Keita Modou Lamin, Ilias Hossain and 6 more

Abstract read
In one paragraph

Article in IJID regions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Isaac OseiMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Baleng Mahama WutorMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Alieu KuyatehMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Ousman BarjoMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Golam SarwarMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Mayowa OmotoshoMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Williams Oluwatosin AdefilaMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Yusuf Abdulsalam OlawaleMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Keita Modou LaminMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Ilias HossainMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Babila G LobgaMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Muhammed WallyMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Morr ChamMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Minteh MolfaMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Rasheed SalaudeenMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.
Grant A MackenzieMedical Research Council Unit The Gambia at London School of Hygiene & Tropical Medicine, Banjul, The Gambia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: There is a lack of data on the time to blood culture positivity (TTP) in pediatric populations in low-income countries. We aimed to assess the host and pathogen factors associated with TTP in children aged under 5 years in rural Gambia. Methods: Between September 2019 and December 2023, we collected blood cultures from children under 5 years with suspected bloodstream infections. We determined the TTP from the time of culture incubation to when bacterial growth was first detected. Results: Overall, 547 invasive bacteria pathogens were evaluated. The median TTP was 19.2 hours and 70%, 76%, 89%, and 96% of cases had TTP at 24, 36, 48, and 72 hours, respectively. Conclusions: In rural Gambia, most blood cultures from pediatric patients would turn positive within 48 hours of incubation. A maximum of 48 hours of observation after the commencement of antibiotic therapy in hospitalized children may be sufficient for clinicians to receive feedback on blood culture results.

Indexed as

Blood culturesBloodstream infectionsChildrenThe GambiaTime-to-positivity

Identifiers

PMID40114912
PMCPMC11923810

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.