ArticlePostepy dermatologii i alergologii2025
TCA chemical peel as facial anti-aging therapy for postmenopausal women: a randomised clinical study.
Article in Postepy dermatologii i alergologii, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: A randomised controlled clinical trial involving a novel trichloroacetic acid (TCA) peel was performed. The experimental group, the placebo group, the staff administering treatments, the persons evaluating intervention results, and the statistical analyst were all blinded. Aim: To assess the efficacy of a novel TCA peel containing urea peroxide 5%, coenzyme Q10 5%, and kojic acid 10% as anti-aging skin therapy for postmenopausal women. Material and methods: Forty-six postmenopausal women at a mean age of 60.63 ±2.6 years were equally and randomly divided into an experimental group (EG; Results: Skin hydration and participants' satisfaction with treatment results measured post-treatment and at month 3 of follow-up were greater in the EG than in the CG. Conclusions: The TCA chemical peel improved facial skin hydration in postmenopausal women, but not skin elasticity. The results of the treatments were rated by the participants as satisfying.Trial Registration no: ISRCTN41899475; doi.org/10.1186/ISRCTN41899475.
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