Evidence map›Paper›PMID 40114727›Full record

ArticleRSC advances2025

RP-HPLC method development and validation for the quantification of prednisolone and salbutamol with their simultaneous removal from water using modified clay-activated carbon adsorbents.

M Ramadan Mahmoud, Samar M Mahgoub, Rania Abdelazeem, Mahmoud M Abdelsatar, Ahmed A Allam, Haifa E Alfassam, Abdelatty M Radalla, Rehab Mahmoud

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M Ramadan MahmoudFaculty of Pharmacy, Al-Azhar University Assiut Egypt.
Samar M MahgoubMaterials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University Beni-Suef Egypt miramar15@yahoo.com.
Rania AbdelazeemEnvironmental Science and Industrial Development Department, Faculty of Postgraduate Studies for Advanced Sciences, Beni-Suef University Beni-Suef 62521 Egypt.
Mahmoud M AbdelsatarDepartment of Geology, Faculty of Science, Beni-Suef University Beni-Suef Egypt mahmoud.abdelstar.1997@gmail.com.
Ahmed A AllamDepartment of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University Riyadh 11623 Saudi Arabia.
Haifa E AlfassamDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University P.O. Box 84428 Riyadh 11671 Saudi Arabia halfassam@pnu.edu.sa.
Abdelatty M RadallaChemistry Department, Faculty of Sciences, Beni-Suef University Beni-Suef Egypt rehabkhaled@science.bsu.edu.eg abdelaty.mohamed@science.bsu.edu.eg.
Rehab MahmoudChemistry Department, Faculty of Sciences, Beni-Suef University Beni-Suef Egypt rehabkhaled@science.bsu.edu.eg abdelaty.mohamed@science.bsu.edu.eg.ORCID https://orcid.org/0000-0003-2274-2016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salbutamol sulfate (SAL) and prednisolone (PRD) are commonly used for treating respiratory and inflammatory conditions, yet they are frequently detected in aquatic ecosystems, posing significant risks to aquatic life and biodiversity. Despite the growing concern over pharmaceutical pollution, there is a lack of reliable and sustainable methods for quantifying these drugs in both pharmaceutical and environmental samples, as well as effective adsorbents for their removal from contaminated water. This study aims to fill this gap by developing a reliable reversed-phase high-performance liquid chromatography (RP-HPLC) method for quantifying SAL and PRD, while also creating an organoclay-activated carbon composite adsorbent for removing these drugs from water. The HPLC method was validated for linearity, precision, accuracy, robustness, and specificity, with detection limits of 1.06 μg mL

Identifiers

PMID40114727
PMCPMC11924354

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.