Evidence map›Paper›PMID 40114677›Full record

ArticleSurgery open science2025

Exploring the dynamics of postoperative steatosis in the regenerating liver: An animal study.

Andrea Lund, Katrine Holm Andersen, Kasper Jarlhelt Andersen, Jakob Kirkegård, Jens Randel Nyengaard, Frank Viborg Mortensen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgery open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea LundDepartment of Surgery, Section for HPB Surgery, Aarhus University Hospital, Aarhus, Denmark.
Katrine Holm AndersenDepartment of Surgery, Section for HPB Surgery, Aarhus University Hospital, Aarhus, Denmark.
Kasper Jarlhelt AndersenDepartment of Surgery, Section for HPB Surgery, Aarhus University Hospital, Aarhus, Denmark.
Jakob KirkegårdDepartment of Surgery, Section for HPB Surgery, Aarhus University Hospital, Aarhus, Denmark.
Jens Randel NyengaardCore Center for Molecular Morphology, Section for Stereology and Microscopy, Aarhus University, Denmark.
Frank Viborg MortensenDepartment of Surgery, Section for HPB Surgery, Aarhus University Hospital, Aarhus, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The rat model of 70 % partial hepatectomy (PH) is commonly used to investigate liver regeneration processes. The aim of this study was to explore the dynamics of hepatic lipid accumulation and its correlation with the proliferation response during the entire regeneration phase after 70 % PH in rats. Methods: Sixty-four rats underwent 70 % PH and were randomly divided into eight groups for evaluation on post-operative day (POD) 1 to 8. Hepatocyte volume, relative lipid content, and lipid volume per hepatocyte were assessed by stereological analysis. Conclusion: Lipid accumulation and proliferation peak and decline concurrently, suggesting a strong correlation.

Indexed as

Hepatic steatosisLipid accumulationLiver regenerationPartial hepatectomyRat

Identifiers

PMID40114677
PMCPMC11924926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.