Evidence map›Paper›PMID 40114578›Full record

ArticleCurrent pharmaceutical design2025

Enhanced Wound Healing with

Anandarajagopal Kalusalingam, Abdullah Khan, Mahibub Mahamadsa Kanakal, Syed Atif Abbas, Chiau Ming Long, Tazneem Bachi, Ching Siang Tan, Abubakar Salam Bawazir, T K Abdul Razak, Roshan Salfi

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Article in Current pharmaceutical design, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Anandarajagopal KalusalingamSchool of Pharmacy, KPJ Healthcare University, Nilai, 71800, Negeri Sembilan, Malaysia.
Abdullah KhanFaculty of Pharmacy, Quest International University, Ipoh, Perak, 30250, Malaysia.
Mahibub Mahamadsa KanakalFaculty of Pharmacy, Quest International University, Ipoh, Perak, 30250, Malaysia.
Syed Atif AbbasFaculty of Pharmacy, Quest International University, Ipoh, Perak, 30250, Malaysia.
Chiau Ming LongDepartment of Medical Sciences, Sunway University, Bandar Sunway, 47500, Selangor Darul Ehsan, Malaysia.
Tazneem BachiDeccan School of Pharmacy, Osmania University, Hyderabad, 500001, Telangana, India.
Ching Siang TanSchool of Pharmacy, KPJ Healthcare University, Nilai, 71800, Negeri Sembilan, Malaysia.
Abubakar Salam BawazirYB Chavan College of Pharmacy, Dr Rafiq Zakaria Campus Rauza Baugh, Aurangabad, 431001, Maharashtra, India.
T K Abdul RazakAPEX Pharma, King Abdullah Economic City, Rabigh, Saudia Arabia.
Roshan SalfiDeccan School of Pharmacy, Osmania University, Hyderabad, 500001, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study explores the formulation and effectiveness of a

objectiveThe ethanolic extract of

methodsCharacterization through GC-MS revealed compounds, such as 2-Heptadecenal and Bicyclo[ 4.1.0]Heptane and 7-Pentyl. FTIR confirmed the successful encapsulation within the phospholipid bilayer, while SEM showed smooth, spherical particles.

resultsThe Box-Behnken design optimized formulation parameters, achieving high yield (92.64%), small particle size (355 nm), and high entrapment efficiency (93.98%).

conclusionThis research highlights the potential of Rhodiola rosea phytosomal gel as an effective wound healing therapy, with future studies suggested for extended stability tests and human skin permeation studies.

Indexed as

Plant ExtractsRhodiolaWound HealingAnimalsGelsMaleRatsRats, WistarGelsPlant ExtractsBox-Behnken designextractionin vivo evaluation.phytosomal gelRhodiola roseawound healing

Identifiers

PMID40114578

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.