Evidence map›Paper›PMID 40114558›Full record

ArticleGut microbes2025

Anti-interleukin-23 treatment linked to improved

Gregory R Madden, Robert Preissner, Saskia Preissner, William A Petri

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Mechanisms ofFrontiers in cellular and infection microbiology · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Gregory R MaddenDivision of Infectious Diseases & International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA.ORCID 0000-0002-5951-3156
Robert PreissnerScience-IT and Institute of Physiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.ORCID 0000-0002-2407-1087
Saskia PreissnerScience-IT and Institute of Physiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.ORCID 0000-0002-3672-0283
William A PetriDivision of Infectious Diseases & International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA, USA.ORCID 0000-0002-7268-1218

Funding

Role of Th17 in Severe and Recurrent C. difficile InfectionR01AI152477 · NIAID · UNIVERSITY OF VIRGINIA · PI PETRI, WILLIAM A, RAMAKRISHNAN, GIRIJA · 2020 to 2025
$7.1M
Role of Type 2 Immunity in Innate Protection from C. difficileR01AI124214 · NIAID · UNIVERSITY OF VIRGINIA · PI William A Petri · 2016 to 2026
$5.4M
Immune profiling to stratify Clostridioides difficile infection outcomesK23AI163368 · NIAID · UNIVERSITY OF VIRGINIA · PI MADDEN, GREGORY RUSSELL · 2021 to 2025
$961k
NIAID NIH HHS K23 AI163368NIAID NIH HHS R01 AI124214NIAID NIH HHS R01 AI152477
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antibodies, MonoclonalClostridioides difficileClostridium InfectionsInterleukin-23AdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAntibodies, MonoclonalInterleukin-23C. difficile infectionClostridioides difficileIL-23interleukin-23monoclonal antibodyretrospective studyTh17 immunity

Identifiers

PMID40114558
PMCPMC11934156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.