Evidence map›Paper›PMID 40114409›Full record

ArticleSubstance use & misuse2025

Contemporaneous Link Between Pain and Craving in Patients Recovering from Prescription Opioid Use Disorder During Residential Treatment.

Daniel J Petrie, Kyler S Knapp, Christopher S Freet, Erin Deneke, Dean Stankoski, Timothy R Brick, H Harrington Cleveland, Scott C Bunce

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Substance use & misuse, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel J PetrieDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-5759-8037
Kyler S KnappSchool of Social Work, The State University of New York at Buffalo, Buffalo, NY, USA.ORCID 0000-0003-4737-4133
Christopher S FreetDepartment of Psychiatry and Behavioural Health, The Pennsylvania State University College of Medicine, Hershey, PA, USA.
Erin DenekeCaron Treatment Centers, Wernersville, PA, USA.
Dean StankoskiDepartment of Psychiatry and Behavioural Health, The Pennsylvania State University College of Medicine, Hershey, PA, USA.
Timothy R BrickDepartment of Human Development and Family Studies, The Pennsylvania State University, University Park, PA, USA.
H Harrington ClevelandDepartment of Human Development and Family Studies, The Pennsylvania State University, University Park, PA, USA.
Scott C BunceDepartment of Psychiatry and Behavioural Health, The Pennsylvania State University College of Medicine, Hershey, PA, USA.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
PREVENTION AND METHODOLOGY TRAINING (PAMT)T32DA017629 · NIDA · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI Eric D Claus, Rina D Eiden · 2005 to 2026
$9.5M
RESEARCH TRAINING ON ALCOHOL ETIOLOGY AND TREATMENTT32AA007583 · NIAAA · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Gregory G Homish, KENNETH E LEONARD · 2000 to 2026
$8.5M
INTERDISCIPLINARY ALCOHOL RESEARCH TRAINING PROGRAMT32AA007453 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKE S.G. MOLINA · 1985 to 2026
$3.7M
Prescription Opioid Dependence Physiology Emotion and Treatment OutcomeR01DA035240 · NIDA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI BUNCE, SCOTT C, MEYER, ROGER EMIL · 2013 to 2015
$1.8M
NCATS NIH HHS UL1 TR002014NIAAA NIH HHS T32 AA007453NIAAA NIH HHS T32 AA007583NIDA NIH HHS R01 DA035240NIDA NIH HHS T32 DA017629
6 · The paper itself

Abstract

objectiveThe study examined the relationship between pain and craving in the daily lives of patients in residential treatment for prescription opioid use disorder (OUD) and the extent to which the contemporaneous assessment-level association between pain and craving was moderated by individuals' average pain levels.

methodsParticipants (

resultsThere was a significant association between assessment-level pain and craving (

conclusionsThese results indicate that the experience of higher-than-usual pain, regardless of individual patients' usual pain levels, is linked to higher contemporaneous craving. This finding supports the importance of assessing and managing pain in the prescription OUD patient's early treatment experience to help reduce craving and its role in return to illicit use.

Indexed as

Chronic PainCravingOpioid-Related DisordersPainResidential TreatmentAdultFemaleHumansMaleMiddle AgedPain MeasurementYoung Adultcravingecological momentary assessment, opioid use disorderpainPrescription opioids

Identifiers

PMID40114409
PMCPMC11999769

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.