Evidence map›Paper›PMID 40114284›Full record

ArticleBMC chemistry2025

Eco-friendly RP-HPLC method for simultaneous determination of water-soluble and fat-soluble vitamins in nano-formula and pharmaceutical dosage forms.

Safaa Hussein Salah El-Din, Amr M Mahmoud, Amany Morsi

Abstract read
In one paragraph

Article in BMC chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Safaa Hussein Salah El-DinEgyptian Drug Authority, Cairo, Egypt.
Amr M MahmoudAnalytical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt. amr.bekhet@pharma.cu.edu.eg.ORCID http://orcid.org/0000-0002-7804-6442
Amany MorsiEgyptian Drug Authority, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A green method for simultaneous determination of water soluble vitamin (vitamin C) and fat soluble vitamin (vitamin A) was developed using reversed phase high performance liquid chromatography technique. The method succeed to separate the water-soluble and fat-soluble vitamins by isocratic elution using Agilent Zorbax octylsilane column (250 × 4.6 mm, 5 μm) in a short single run. The proposed mobile phase consisted of buffer (10 mM potassium dihydrogen phosphate and 3 mM hexane sulfonic acid sodium salt), pH adjusted to 2.5 using orthophosphoric acid and methanol in a ratio (8:92 v/v) with flow rate 1.0 mL.min

Indexed as

Fat soluble vitaminIsocratic elutionRP-HPLCVitamin AVitamin CWater soluble vitamin

Identifiers

PMID40114284
PMCPMC11927356

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.