ReviewChild and adolescent psychiatry and mental health2025
Global prevalence of nocturnal enuresis and associated factors among children and adolescents: a systematic review and meta-analysis.
Review in Child and adolescent psychiatry and mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence, risk factors, and psychosocial impacts of enuresis in Saudi primary school-aged children: a systematic review and meta-analysis.The Pan African medical journal · 2026Pooled it
- Efficacy and safety of first-line therapies and first-line-based combination therapies for monosymptomatic nocturnal enuresis in children: a network meta-analysis.Pediatric nephrology (Berlin, Germany) · 2026Review
- Enuresis in Children.Indian journal of pediatrics · 2026Review
- Article
- Association between mental health problems and nocturnal enuresis among children and adolescents in Ethiopia.Discover mental health · 2026Article
- Drug-induced urinary incontinence in pediatric patients: A disproportionality analysis of the FDA Adverse Event Reporting System.Medicine · 2026Article
- Daytime Bladder Control Status in Toddlerhood Is Associated With Subsequent Bedwetting in Preschool Years: A Nationwide Cohort Study of Over 30 000 Japanese Children.International journal of urology : official journal of the Japanese Urological Association · 2026Article
- Prevalence and Factors Associated with Nocturnal Enuresis Among Children Aged 6-14 Years in Mogadishu: A Hospital-Based Cross-Sectional Study.Pediatric health, medicine and therapeutics · 2026Article
- Stratifying Treatment-Resistant Monosymptomatic Nocturnal Enuresis: Identifying the Subgroup Most Responsive to Biofeedback Therapy.Diagnostics (Basel, Switzerland) · 2025Article
- Sleep Parameters and Quality of Life in Children with Monosymptomatic Nocturnal Enuresis: Association, Prediction and Moderation Analysis.International journal of environmental research and public health · 2025Article
- Modern management of pediatric nocturnal enuresis: Evidence-based treatment and practical guidance.Tzu chi medical journalReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNocturnal enuresis (NE), a prevalent childhood condition associated with significant emotional morbidity, including anxiety, guilt, and diminished self-esteem. Notably, NE exhibits substantial variability in prevalence across diverse geographical and sociocultural contexts ranging from 2 to 75%, highlighting the influence of environmental and societal factors. The associated social stigma exacerbates emotional distress, negatively impacting self-perception and overall quality of life. This systematic review and meta-analysis seek to synthesize global epidemiological data on NE, accounting for inter-country prevalence variations, and to elucidate its associated factors, thereby informing the development of culturally sensitive and effective intervention strategies.
methodsAll observational quantitative research articles conducted among children and adolescents in the world were included. We used PubMed Central, Cochrane Library, Scopus, and Google Scholar searching databases. The study quality was checked using the Newcastle - Ottawa Scale. Then I
resultsIn the final analysis, one hundred twenty-eight studies involving 445,242 individuals in 39 countries. The overall pooled prevalence of Nocturnal enuresis among children and adolescents was 7.2% (95% CI: 6.2-8.1%). Positive family history AOR 1.49 (95% CI: 1.26-1.71), positive urinary tract infection AOR; 3.89, 95% CI (2.93-4.46), parental death AOR = 1.93 (95% CI: 1.73-2.12), first birth order AOR 0.5 (95% CI: 0.37-0.62), and male sex AOR 1.63; 95% CI (1.31-1.94 were the significant associated factors with Nocturnal enuresis among children and adolescent.
conclusionThe study found that nocturnal enuresis affects approximately 7.2% of children and adolescents. Family history, urinary tract infection, parental death, birth order, and sex were statistically significant factors. It is recommended that healthcare providers should implement routine screening for nocturnal enuresis, particularly for children with known risk factors such as family history and urinary tract infections, and the development of targeted interventions and support mechanisms should be prioritized, considering the significant impacts of these factors among children and adolescents.
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