Evidence map›Paper›PMID 40114236›Full record

ReviewHealth research policy and systems2025

A bespoke rapid evidence review process engaging stakeholders for supporting evolving and time-sensitive policy and clinical decision-making: reflection and lessons learned from the Wales COVID-19 Evidence Centre 2021-2023.

Ruth Lewis, Alison Cooper, David Jarrom, Mala Mann, Rebecca-Jane Law, Deborah Edwards, Judith Carrier, Hannah Shaw, Tom Winfield, Llinos Haf Spencer and 8 more

Abstract readReview
In one paragraph

Review in Health research policy and systems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ruth LewisWales COVID-19 Evidence Centre, Health and Care Research Wales, Welsh Government, Cardiff, United Kingdom. r.lewis@bangor.ac.uk.ORCID http://orcid.org/0000-0003-0745-995X
Alison CooperWales COVID-19 Evidence Centre, Health and Care Research Wales, Welsh Government, Cardiff, United Kingdom.
David JarromHealth Technology Wales (HTW), Cardiff, United Kingdom.
Mala MannSpecialist Unit for Review Evidence (SURE), Cardiff University, Cardiff, United Kingdom.
Rebecca-Jane LawTechnical Advisory Cell, Welsh Government, Cardiff, United Kingdom.
Deborah EdwardsWales Centre for Evidence Based Care, School of Healthcare Sciences, Cardiff University, Cardiff, United Kingdom.
Judith CarrierWales Centre for Evidence Based Care, School of Healthcare Sciences, Cardiff University, Cardiff, United Kingdom.
Hannah ShawPublic Health Wales, Cardiff, United Kingdom.
Tom WinfieldHealth Technology Wales (HTW), Cardiff, United Kingdom.
Llinos Haf SpencerCentre for Health Economics & Medicines Evaluation, Bangor Institute for Health & Medical Research, School of Health Sciences, Bangor University, Bangor, United Kingdom.
Jane NoyesBangor Institute for Health & Medical Research, School of Health Sciences, Bangor University, Bangor, United Kingdom.
Helen MorganSpecialist Unit for Review Evidence (SURE), Cardiff University, Cardiff, United Kingdom.
Jennifer WashingtonHealth Technology Wales (HTW), Cardiff, United Kingdom.
Elise HaslerHealth Technology Wales (HTW), Cardiff, United Kingdom.
Micaela GalWales COVID-19 Evidence Centre, Health and Care Research Wales, Welsh Government, Cardiff, United Kingdom.
Elizabeth DoeWales COVID-19 Evidence Centre, Health and Care Research Wales, Welsh Government, Cardiff, United Kingdom.
Natalie Joseph-WilliamsWales COVID-19 Evidence Centre, Health and Care Research Wales, Welsh Government, Cardiff, United Kingdom.
Adrian EdwardsWales COVID-19 Evidence Centre, Health and Care Research Wales, Welsh Government, Cardiff, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic presented policymakers with time-sensitive decision problems and a rapidly increasing volume of research, not all of which was robust, or relevant to local contexts. A bespoke evidence review process supporting stakeholder engagement was developed as part of the Wales COVID-19 Evidence Centre (WCEC), which could flexibly react to the needs of decision-makers, to address urgent requests within days or months as required.

aimsTo describe and appraise the WCEC review process and methods and identify key learning points.

methodsThree types of rapid review products were used, which could accommodate the breadth of decision problems and topics covered. Stakeholder (including public) engagement was integrated from the onset and supported throughout. The methods used were tailored depending on the needs of the decision-maker, type of research question, timeframe, and volume and type of evidence. We appraised the overall process and compared the methods used with the most recent and relevant best practice guidance.

resultsThe remote collaboration between research teams, establishing a clear pathway to impact upfront, and the strong stakeholder involvement embedded in the review process were considered particular strengths. Several key learning points were identified, which focused on: enhancing stakeholders' abilities to identify focused policy-relevant research questions; the collection and storage of review protocols at a central location; tightening quality assurance process regarding study selection, data extraction and quality assessment; adequate reporting of methodological shortcuts and understanding by stakeholders; piloting of an algorithm for assigning study design descriptors, and a single quality assessment tool covering multiple study designs; and incorporate, where appropriate an assessment of the confidence in the overall body of evidence using GRADE or similar framework.

conclusionsThe review process enabled a high volume of questions that were directly relevant to policy and clinical decision making to be addressed in a timely manner using a transparent and tailored approach.

Indexed as

Clinical Decision-MakingCOVID-19Health PolicyPolicy MakingStakeholder ParticipationDecision MakingEvidence-Based MedicineHumansPandemicsSARS-CoV-2WalesCOVID-19Evidence synthesis programmePandemicRapid reviewsStakeholder involvement

Identifiers

PMID40114236
PMCPMC11927267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.