Evidence map›Paper›PMID 40114162›Full record

Trial reportBMC complementary medicine and therapies2025

Effect of single or multi-period use of transcutaneous acupoint electrical stimulation on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: a prospective randomized double-blind trial.

Li-Dan Jin, Wan Lei, Jing Xu, Li Xing, Yao-Hua Shen, Su-Feng Lin, Yu-Fei Chen, Ting-Ting He, Xi-Yang Wang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Li-Dan JinDepartment of Anesthesiology, Linping District Maternal and Children Health Care Hospital, Hangzhou, 311199, China. lidanjin@zju.edu.cn.
Wan LeiDepartment of Anesthesiology, Linping District Maternal and Children Health Care Hospital, Hangzhou, 311199, China.
Jing XuDepartment of Anesthesiology, Linping District Maternal and Children Health Care Hospital, Hangzhou, 311199, China.
Li XingDepartment of Anesthesiology, Linping District Maternal and Children Health Care Hospital, Hangzhou, 311199, China.
Yao-Hua ShenDepartment of Anesthesiology, Linping District Maternal and Children Health Care Hospital, Hangzhou, 311199, China.
Su-Feng LinDepartment of Anesthesiology, Linping District Maternal and Children Health Care Hospital, Hangzhou, 311199, China.
Yu-Fei ChenDepartment of Anesthesiology, Linping District Maternal and Children Health Care Hospital, Hangzhou, 311199, China.
Ting-Ting HeDepartment of Anesthesiology, Linping District Maternal and Children Health Care Hospital, Hangzhou, 311199, China.
Xi-Yang WangDepartment of Gynecology, Linping District Maternal and Children Health Care Hospital, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the efficacy of different periods for the prevention of postoperative nausea and vomiting (PONV) in patients undergoing gynecological laparoscopy with transcutaneous electrical acupoint stimulation (TEAS).

designProspective, randomized, double-blind trial.

settingAn academic medical canter specializing in the care of women and children. POPULATION OR SAMPLE: A total of 120 women were enrolled.

methodsPatients were randomly allocated to three groups: a single-period TEAS group (Group S, n = 40), a multi-period TEAS group (Group M, n = 40) and a non-stimulation control group (Group C, n = 40). TEAS was applied at specific acupuncture points preoperatively and postoperatively.

main outcome measuresThe primary outcome was the incidence and severity of PONV during the 48 h after surgery and the secondary outcomes included pain, early recovery after surgery, and complication.

resultsWithin postoperative 0-2 h, 4-12 h, group M had less frequency and lower scores for nausea compared with group C and group S had only less frequency of nausea compared with group C at 4-12 h postoperatively. The frequency and severity of vomiting for group M were less than group S in the postoperative 2-4 h. Group M mitigated pain and reduced the rescue antiemetic compared to group S.

conclusionMultiple-period TEAS provides greater efficacy and a longer duration of action than single-period TEAS. It effectively reduces PONV in patients undergoing gynecological laparoscopic surgery which could be a new option in multimodal prophylactic antiemetic regimes for perioperative undergoing gynecological laparoscopic surgery.

trial registrationChinese Clinical Trials Registry, No. ChiCTR2200065802, Registered 15/11/2022. https//www.chictr.org.cn/bin/project/edit? pid=175,377.

Indexed as

Acupuncture PointsGynecologic Surgical ProceduresLaparoscopyPostoperative Nausea and VomitingTranscutaneous Electric Nerve StimulationAdultDouble-Blind MethodFemaleHumansMiddle AgedProspective StudiesYoung AdultAcupuncture pointsGynecological laparoscopyHegu (L14)Neiguan (PC6)Postoperative nausea and vomitingTranscutaneous electric acupoint stimulation

Identifiers

PMID40114162
PMCPMC11927246

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.