Evidence map›Paper›PMID 40114138›Full record

ArticleMalaria journal2025

Acceptance of a malaria vaccine among caregivers of sick children under 5 years of age in Burundi.

Eric Ntihebuwayo, Manassé Nimpagaritse, Thomas Bizimana, Stany Banzimana, Dieudonné Kabura, Pierre Sinarinzi, Domina Asingizwe

Abstract read
In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eric NtihebuwayoEAC Regional Centre of Excellence for Vaccines, Immunization, and Health Supply Chain Management, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Manassé NimpagaritseInstitut National de Santé Publique, Bujumbura, Burundi.
Thomas BizimanaEAC Regional Centre of Excellence for Vaccines, Immunization, and Health Supply Chain Management, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Stany BanzimanaEAC Regional Centre of Excellence for Vaccines, Immunization, and Health Supply Chain Management, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda.
Dieudonné KaburaInstitut National de Santé Publique, Bujumbura, Burundi.
Pierre SinarinziNational Malaria Control Program (NMCP), Bujumbura, Burundi.
Domina AsingizweEAC Regional Centre of Excellence for Vaccines, Immunization, and Health Supply Chain Management, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda. adomina23@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalaria poses a significant public health burden globally, particularly in Burundi, where it is the leading cause of mortality and morbidity. To eliminate malaria, the malaria vaccine will be introduced in childhood vaccination. However, the information on malaria vaccine acceptance is limited. Therefore, this study investigates malaria vaccine acceptance and associated factors in Burundi.

methodsThis was a descriptive cross-sectional study that involved caregivers of sick children under 5 years old to assess the acceptability of the malaria vaccine. A questionnaire was used to collect data, and SPSS was used to analyse data and identify factors significantly associated with malaria vaccine acceptance.

resultsOverall, 405 (90.6%) participants indicated they would accept a malaria vaccine for their children under 5 years. The predictive factors that are significantly associated with the acceptance of the malaria vaccine include the caregivers' knowledge regarding the malaria vaccine (OR = 10.326, P-value = 0.035), the caregivers' employment (OR = 6.088, P-value = 0.02), and previous experience with childhood vaccination (OR = 3.145, P-value = 0.004).

conclusionThis study shows a high proportion of caregivers' willingness to accept the malaria vaccine. Factors including caregivers' employment, prior childhood vaccination experience, and awareness of the malaria vaccine significantly influence acceptance. These findings highlight the need for targeted awareness campaigns to increase awareness, thus, the potential for widespread vaccine adoption. Consequently, building on existing trust in childhood vaccinations, policymakers should prioritize targeted public health interventions that address knowledge gaps and concerns, ultimately contributing to malaria prevention and control efforts.

Indexed as

CaregiversHealth Knowledge, Attitudes, PracticeMalariaMalaria VaccinesPatient Acceptance of Health CareVaccinationAdultBurundiChild, PreschoolCross-Sectional StudiesFemaleHumansInfantMaleMiddle AgedSurveys and QuestionnairesMalaria VaccinesAcceptanceBurundiCaregiversMalaria vaccineSick children under 5 years

Identifiers

PMID40114138
PMCPMC11924659

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.