Evidence map›Paper›PMID 40114010›Full record

ReviewNature reviews. Neuroscience2025

Disentangling sources of variability in decision-making.

Jade S Duffy, Mark A Bellgrove, Peter R Murphy, Redmond G O'Connell

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jade S DuffyTrinity College Institute of Neuroscience and School of Psychology, Trinity College Dublin, Dublin, Ireland.ORCID http://orcid.org/0000-0001-6650-0022
Mark A BellgroveSchool of Psychological Sciences and Turner Institute for Brain and Mental Health, Monash University, Melbourne, Victoria, Australia.ORCID http://orcid.org/0000-0003-0186-8349
Peter R Murphy *Department of Psychology, Maynooth University, Kildare, Ireland.ORCID http://orcid.org/0000-0003-1963-185X
Redmond G O'Connell *Trinity College Institute of Neuroscience and School of Psychology, Trinity College Dublin, Dublin, Ireland. reoconne@tcd.ie.ORCID http://orcid.org/0000-0001-6949-2793

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Even the most highly-trained observers presented with identical choice-relevant stimuli will reliably exhibit substantial trial-to-trial variability in the timing and accuracy of their choices. Despite being a pervasive feature of choice behaviour and a prominent phenotype for numerous clinical disorders, the capability to disentangle the sources of such intra-individual variability (IIV) remains limited. In principle, computational models of decision-making offer a means of parsing and estimating these sources, but methodological limitations have prevented this potential from being fully realized in practice. In this Review, we first discuss current limitations of algorithmic models for understanding variability in decision-making behaviour. We then highlight recent advances in behavioural paradigm design, novel analyses of cross-trial behavioural and neural dynamics, and the development of neurally grounded computational models that are now making it possible to link distinct components of IIV to well-defined neural processes. Taken together, we demonstrate how these methods are opening up new avenues for systematically analysing the neural origins of IIV, paving the way for a more refined, holistic understanding of decision-making in health and disease.

Indexed as

BrainChoice BehaviorDecision MakingModels, NeurologicalAnimalsHumans

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.