Evidence map›Paper›PMID 40113828›Full record

ArticleNPJ science of food2025

Protective effects of human breast milk-derived exosomes on inflammatory bowel disease through modulation of immune cells.

Ki-Uk Kim, Jisu Kim, Hyunjun Jang, Kang Bin Dan, Bo Kyeong Kim, Yong Woo Ji, Dae Yong Yi, Hyeyoung Min

Abstract read
In one paragraph

Article in NPJ science of food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ki-Uk KimCollege of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.
Jisu KimCollege of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.ORCID http://orcid.org/0000-0002-4361-5895
Hyunjun JangCollege of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.
Kang Bin DanCollege of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.
Bo Kyeong KimCollege of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea.
Yong Woo JiInstitute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, 03722, Republic of Korea.
Dae Yong YiDepartment of Pediatrics, Chung-Ang University Hospital, Seoul, 06973, Republic of Korea.
Hyeyoung MinCollege of Pharmacy, Chung-Ang University, Seoul, 06974, Republic of Korea. hymin@cau.ac.kr.

Funding

National Research Foundation of Korea (NRF) NRF-2021R1F1A1061287
6 · The paper itself

Abstract

Human breast milk (HBM)-derived exosomes play a crucial role not only in infant nutrition but also in modulating inflammation, immunity, and epithelial cell protection. This study investigated how HBM-derived exosomes regulate immune cell development and function. The exosomes promoted the differentiation of naïve CD4

Identifiers

PMID40113828
PMCPMC11926119

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.