Evidence map›Paper›PMID 40113819›Full record

ArticleScientific reports2025

High proportions of multidrug-resistant Klebsiella pneumoniae isolates in community-acquired infections, Brazil.

Adriano de Souza Santos Monteiro, Márcio de Oliveira Silva, Vívian Santos Galvão, Adriele Pinheiro Bomfim, Lorena Galvão de Araújo, Camila Maria Piñeiro Silva, Maria Goreth Barberino, Edilane Lins Gouveia, Soraia Machado Cordeiro, Joice Neves Reis

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Biofilm-Forming Capacity andAntibiotics (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Observational
  7. Recurrent Urinary Tract Infection Caused by Multidrug-ResistantCase reports in infectious diseases · 2026
    Article
  8. Article
  9. Circulation of ESBL-producingFrontiers in public health · 2026
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adriano de Souza Santos MonteiroPostgraduate Course in Biotechnology in Health and Investigative Medicine, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, BA, Brazil.ORCID http://orcid.org/0000-0001-6675-4217
Márcio de Oliveira SilvaPostgraduate Course in Biotechnology in Health and Investigative Medicine, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, BA, Brazil.
Vívian Santos GalvãoPostgraduate Program in Pharmacy, Faculty of Pharmacy, Federal University of Bahia, Salvador, BA, Brazil.ORCID http://orcid.org/0000-0001-6796-0610
Adriele Pinheiro BomfimPostgraduate Program in Pharmacy, Faculty of Pharmacy, Federal University of Bahia, Salvador, BA, Brazil.ORCID http://orcid.org/0000-0002-6180-5764
Lorena Galvão de AraújoPostgraduate Course in Biotechnology in Health and Investigative Medicine, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, BA, Brazil.
Camila Maria Piñeiro SilvaFaculty of Pharmacy, Federal University of Bahia, Ondina, Salvador, 40170-115, BA, Brazil.
Maria Goreth BarberinoSão Rafael Hospital, Salvador, BA, Brazil.ORCID http://orcid.org/0000-0002-7858-0768
Edilane Lins GouveiaBahia Hospital, Salvador, BA, Brazil.
Soraia Machado CordeiroFaculty of Pharmacy, Federal University of Bahia, Ondina, Salvador, 40170-115, BA, Brazil.ORCID http://orcid.org/0000-0001-5320-892X
Joice Neves ReisPostgraduate Course in Biotechnology in Health and Investigative Medicine, Gonçalo Moniz Institute, Oswaldo Cruz Foundation, Salvador, BA, Brazil. joice@ufba.br.ORCID http://orcid.org/0000-0001-5273-2658

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 309564/2022-0Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado da Bahia PP-SUS0014/2018Instituto Nacional de Pesquisa em Resistência Antimicrobiana -INPRA CNPq 465718/2014-0
6 · The paper itself

Abstract

Klebsiella pneumoniae is one of the leading causes of bloodstream (BSI) and urinary tract infections (UTI), but limited data is available regarding community-acquired (CA) infections. This study characterized the clinical aspects of CA-BSI and CA-UTI caused by K. pneumoniae and the molecular features of isolates, including their resistance profiles. Sixty-five isolates (CA-BSI, n = 24; CA-UTI, n = 41) underwent antimicrobial susceptibility testing, β-lactamase and virulence gene assessment, capsular genotyping, and molecular typing. Older age, male gender, and comorbidities, particularly kidney disease, were significantly associated with CA-BSI. The MDR and carbapenem resistance rates for K. pneumoniae from CA infections were 24.6% and 4.6%, respectively. CA-BSI isolates were more antibiotic-resistant and had a higher proportion of ESBL-producing (37.5% versus 9.8%) and MDR isolates (45.8% versus 12.2%) than CA-UTI. The bla

Indexed as

Community-Acquired InfectionsDrug Resistance, Multiple, BacterialKlebsiella InfectionsKlebsiella pneumoniaeAdultAgedAged, 80 and overAnti-Bacterial Agentsbeta-LactamasesBrazilFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedUrinary Tract InfectionsAnti-Bacterial Agentsbeta-LactamasesAntimicrobial resistanceBloodstream infectionsCommunity-acquiredHigh-risk clonesKlebsiella pneumoniaeUrinary tract infections

Identifiers

PMID40113819
PMCPMC11926192

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.