Evidence map›Paper›PMID 40113809›Full record

ArticleNature communications2025

Injectable bioadhesive and lubricating hydrogel with polyphenol mediated single atom nanozyme for rheumatoid arthritis therapy.

Huan He, Qin Zhang, Yiming Zhang, Shuxin Qu, Bin Li, Jun Lin, Xiong Lu, Chaoming Xie

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
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  3. Liquid-Responsive Shape-Memory Nanofiber-Reinforced Scaffolds for Cartilage Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huan He *Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.
Qin Zhang *Department of Orthopaedics, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Medical Center of Soochow University, Suzhou, 215000, Jiangsu, P.R. China.
Yiming Zhang *Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.
Shuxin QuInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China.
Bin LiMedical 3D Printing Center, Orthopedic Institute, Department of Orthopedic Surgery, The First Affiliated Hospital, MOE Key Laboratory of Geriatric Diseases and Immunology, School of Basic Medical Sciences, Suzhou Medical College, Soochow University, Suzhou, Jiangsu, 215000, P.R. China. binli@suda.edu.cn.ORCID http://orcid.org/0000-0001-8516-9953
Jun LinDepartment of Orthopaedics, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Medical Center of Soochow University, Suzhou, 215000, Jiangsu, P.R. China. linjun@suda.edu.cn.ORCID http://orcid.org/0000-0002-8094-5826
Xiong LuInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China. luxiong_2004@163.com.ORCID http://orcid.org/0000-0001-6367-430X
Chaoming XieInstitute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University, Chengdu, 610031, Sichuan, China. xie@swjtu.edu.cn.ORCID http://orcid.org/0000-0002-6916-675X

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32471392National Natural Science Foundation of China (National Science Foundation of China) 52035012National Natural Science Foundation of China (National Science Foundation of China) 82172387,82372371
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a common chronic autoimmune condition accompanied by lubrication dysfunction, inflammatory infiltration, and cartilage wear. Long-term improvements in joint lubrication, inflammation elimination, and worn cartilage repair are crucial for effective RA treatment. Herein, we present an injectable bioadhesive and lubricating hydrogel containing a dopamine-modified hyaluronic acid (DA-HA) network, sulfonated hyaluronic acid (SO

Indexed as

Arthritis, RheumatoidHydrogelsPolyphenolsAnilidesAnimalsCartilageCartilage, ArticularChondrocytesCopperGraphiteHumansHyaluronic AcidLubricationMaleMesenchymal Stem CellsMiceAnilidesCopperGraphiteHyaluronic AcidHydrogelskartogeninPhthalic AcidsPolyphenols

Identifiers

PMID40113809
PMCPMC11926226

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.