Evidence map›Paper›PMID 40113638›Full record

ReviewFamilial cancer2025

The current status of care for families with Lynch syndrome in China.

Baoshuai Liu, Shouyu Pan, Xian Hua Gao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Familial cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Baoshuai LiuDepartment of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.
Shouyu PanDepartment of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, China.
Xian Hua GaoDepartment of Colorectal Surgery, Changhai Hospital, Naval Medical University, Shanghai, China. gxh505@126.com.

Funding

National Key R&D Program of China 2022YFC2503701National Natural Science Foundation of China 82372903Shanghai Municipal Health Commission's special project for clinical research in the health industry 202240350
6 · The paper itself

Abstract

Lynch syndrome is one of the most common hereditary cancer predisposition syndromes, which is caused by germline pathogenic variants in mismatch repair genes. It is associated with increased risks of colorectal cancer, endometrial cancer and various other types of cancer. With the rapid development in economy, medicine and genetic tests technology in recent decades, China had achieved significant advancements in the screening, diagnosis and treatment of Lynch syndrome. However, there are still a lot of challenges remaining unresolved. The major challenges include inconsistent access to genetic tests and counseling, regional disparities in healthcare quality, and limited implementation of clinical guidelines. This review will focus on the Chinese current status in the screening of Lynch syndrome, cancer surveillance, preventive measures, patients' willingness to take genetic tests and share genetic information, insurance coverage of medical cost, and national collaboration. At the end, we also summarize the major current research themes in Lynch syndrome in China.

Indexed as

Colorectal Neoplasms, Hereditary NonpolyposisGenetic TestingChinaEarly Detection of CancerFemaleGenetic CounselingGenetic Predisposition to DiseaseHumansDeficient mismatch repair (dMMR)Genetic testsLynch syndromeMicrosatellite instability (MSI)ResearchScreening

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.