Evidence map›Paper›PMID 40113451›Full record

ArticleOrthopaedic surgery2025

Establishing a Staging System for Adjacent Segment Disease and Exploring Its Significance in Guiding Surgical Decisions: A Retrospective Study.

Changpeng Qu, Jianwei Guo, Hao Tao, Chuanli Zhou, Kai Zhu, Yihao Sun, Lei Li, Zhiming Liu, Hao Zhang, Xuexiao Ma

Abstract read
In one paragraph

Article in Orthopaedic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Changpeng QuThe Affiliated Hospital of Qingdao University, Department of Spinal Surgery, Qingdao, Shandong, China.ORCID https://orcid.org/0009-0009-4686-721X
Jianwei GuoThe Affiliated Hospital of Qingdao University, Department of Spinal Surgery, Qingdao, Shandong, China.ORCID https://orcid.org/0000-0003-2167-0487
Hao TaoThe Affiliated Hospital of Qingdao University, Department of Trauma Surgery, Qingdao, Shandong, China.
Chuanli ZhouThe Affiliated Hospital of Qingdao University, Department of Spinal Surgery, Qingdao, Shandong, China.
Kai ZhuThe Affiliated Hospital of Qingdao University, Department of Spinal Surgery, Qingdao, Shandong, China.
Yihao SunThe Affiliated Hospital of Qingdao University, Department of Spinal Surgery, Qingdao, Shandong, China.
Lei LiThe Affiliated Hospital of Qingdao University, Department of Spinal Surgery, Qingdao, Shandong, China.
Zhiming LiuThe Affiliated Hospital of Qingdao University, Department of Spinal Surgery, Qingdao, Shandong, China.
Hao ZhangThe Affiliated Hospital of Qingdao University, Department of Spinal Surgery, Qingdao, Shandong, China.ORCID https://orcid.org/0000-0003-1974-1311
Xuexiao MaThe Affiliated Hospital of Qingdao University, Department of Spinal Surgery, Qingdao, Shandong, China.ORCID https://orcid.org/0000-0002-0967-6424

Funding

National Natural Science Foundation of China 82100940Qingdao Municipal Science and Technology Bureau 23-2-8-smjk-7-nsh
6 · The paper itself

Abstract

objectiveThe degeneration characteristics of adjacent segment disease are complex. Improper surgical planning has caused unnecessary surgical trauma and costs. The purpose of this study was to establish a staging system for adjacent segment disease and evaluate its guiding significance for surgical decisions in adjacent segment disease.

methodsA retrospective study was performed on 103 patients with adjacent segment disease who underwent treatment between January 2017 and January 2023. Based on radiological findings, adjacent segment disease was categorized into four stages, with no cases identified in Stage IV. Patients were divided into four intervention groups: Group A (control group, traditional posterior lumbar fusion with rod-screw revision), Group B (Stage I, percutaneous endoscopic decompression), Group C (Stage II, oblique lumbar interbody fusion), and Group D (Stage III, cortical bone trajectory screws with posterior lumbar interbody fusion). Clinical and radiological outcomes were evaluated postoperatively, at 3 months, and at 12 months. Statistical analysis was conducted using t-tests, Mann-Whitney U tests, chi-square tests, and Spearman's correlation.

resultsSurgical expenses, duration, estimated blood loss, postoperative hospital stays, disc height index, and Pfirrmann grading all demonstrated significant correlations with the established grading system (p < 0.05). Patients achieved favorable clinical outcomes. Specifically, Groups B, C, and D showed earlier functional recovery compared to Group A, with Groups B and C experiencing more rapid relief from low back pain. Furthermore, Groups B, C, and D had shorter surgical times and reduced blood loss, while Groups B and C also incurred lower surgical costs and shorter hospital stays (p < 0.05).

conclusionThe new grading system, developed based on the characteristics of adjacent segment degeneration, showed excellent surgical adaptability, despite varying degrees of correlation across different factors. This system was closely linked to the degree of intervertebral disc degeneration and the intervertebral disc height index. All patients achieved favorable surgical outcomes, suggesting that this grading system could provide valuable guidance in making surgical treatment decisions.

Indexed as

Clinical Decision-MakingIntervertebral Disc DegenerationLumbar VertebraeSpinal FusionAdultAgedDecompression, SurgicalFemaleHumansMaleMiddle AgedRetrospective Studiesadjacent segment diseasedisease stagingminimally invasive surgeryrevision surgery

Identifiers

PMID40113451
PMCPMC12050183

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.