Evidence map›Paper›PMID 40113219›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Bioanalytic Hybrid System Merging 3-Dimensional Cell Culture and Chromatographic Precision for Unprecedented Preclinical Insights in Molecular Imaging.

Verena Pichler, Verena Schwingenschlögl-Maisetschläger, Irem Duman, Xavier Monforte, Stefanie Ponti, Lukas Zimmermann, Elma Joldic, Monika Dumanic, Chrysoula Vraka, Marcus Hacker and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Verena PichlerDepartment of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria; verena.pichler@univie.ac.at.
Verena Schwingenschlögl-MaisetschlägerDepartment of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria.
Irem DumanDepartment of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria.
Xavier MonforteDepartment of Life Science Engineering, University of Applied Sciences Technikum Wien, Vienna, Austria.
Stefanie PontiDepartment of Biomedical-Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Lukas ZimmermannDivision of Medical Radiation Physics, Department of Radiation Oncology, Medical University of Vienna, Vienna, Austria; and.
Elma JoldicDepartment of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria.
Monika DumanicDepartment of Biomedical-Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Chrysoula VrakaDepartment of Biomedical-Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Marcus HackerDepartment of Biomedical-Imaging and Image-Guided Therapy, Medical University of Vienna, Vienna, Austria.
Christian KrauleDOC medikus GmbH, Krems, Austria.
Andreas Herbert Teuschl-WollerDepartment of Life Science Engineering, University of Applied Sciences Technikum Wien, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We introduce a unique bioanalytic hybrid system for the preclinical assessment of radiotracer candidates, combining a 3-dimensional cell culture on an artificial extracellular matrix functioning as a stationary phase and a chromatographiclike system array.

Indexed as

Cell Culture TechniquesCell Culture Techniques, Three DimensionalChromatographyMolecular ImagingAnimalsHumansPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRadiopharmaceuticalsartificial extracellular matrixradiotracer developmenttissue engineering

Identifiers

PMID40113219
PMCPMC12051762

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.