Evidence map›Paper›PMID 40113172›Full record

Trial reportThe Journal of nutrition2025

Sowing the Seeds of Taste? A Novel Approach to Investigate the Impact of Early Sweet Exposure on Children's Dietary Taste Patterns from 12 to 36 Mo.

Carina Mueller, Monica Mars, Gertrude G Zeinstra, Corine Perenboom, Ciarán G Forde, Gerry Jager

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The Journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03348176 (The What and How in Weaning), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03348176 nacompletednot on this map

The What and How in Weaning: A Randomized Controlled Trial to Assess the Effects of Vegetable-exposure and Responsive Feeding on Vegetable Acceptance in Infants and Toddlers

TypeinterventionalSponsorUniversiteit LeidenRan2016 to 2020Enrolled255ConditionsVegetable Acceptance in Early Childhood, Childhood Obesity, Childhood OverweightArmsVegetable exposure, VIPP-Feeding Infants, Control
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carina MuellerDivision of Human Nutrition and Health, Wageningen University and Research, Wageningen, The Netherlands.
Monica MarsDivision of Human Nutrition and Health, Wageningen University and Research, Wageningen, The Netherlands.
Gertrude G ZeinstraWageningen Food & Biobased Research, Wageningen University and Research, Wageningen, The Netherlands.
Corine PerenboomDivision of Human Nutrition and Health, Wageningen University and Research, Wageningen, The Netherlands.
Ciarán G FordeDivision of Human Nutrition and Health, Wageningen University and Research, Wageningen, The Netherlands.
Gerry JagerDivision of Human Nutrition and Health, Wageningen University and Research, Wageningen, The Netherlands. Electronic address: gerry.jager@wur.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly food experiences shape children's eating behavior. Whether initiating complementary feeding (CF) with sweet-tasting foods impacts the taste of later dietary patterns remains unknown. This study combined a quantitative taste intensity database with dietary assessment methods to investigate this.

objectivesThis study aims to investigate whether initiating CF in infants with sweet compared with neutral-tasting foods leads to different dietary taste patterns at 12-36 mo.

methodsA total of 246 Dutch infants (age 20.2 ± 1.8 wk, 129 girls) participated in an randomized control trial; they received either sweet-tasting (n = 125) or neutral-tasting (n = 121) fruit and vegetable purees during the first 15 d of initial CF. Dietary intake was assessed at 12, 18, 24, and 36 mo using 3 24-h recalls. Reported foods (n = 1277) were grouped into 5 clusters-"sour-sweet," "sweet-fatty," "fatty-salty," "fatty," and "neutral" tasting foods-based on their taste intensity values using K-means clustering. Dietary taste patterns were calculated as the average daily intake of energy (%kcal) and weight (%grams) from each taste cluster and compared between intervention groups.

resultsOverall, children's energy intake from neutral-tasting foods decreased from 61% ± 11% at 12 mo to 44% ± 12% at 36 mo (P < 0.001). Weight intake from neutral foods also declined (from 74% ± 9% to 62% ± 13%, P < 0.001). Conversely, children's energy intake from sweet-fatty, fatty-salty, and fatty foods increased significantly over the study period (from 12% ± 7% to 21% ± 10%, from 8% ± 6% to 13% ± 7%, and from 7% ± 5% to 11% ± 6%, respectively, all P ≤ 0.01). No differences were observed between the 2 intervention groups.

conclusionsOverall, children's diets became more diverse and intense in taste but exposure to sweet taste during early CF did not influence the dietary taste patterns in later childhood. TRIAL REGISTRATION NUMBER: This trial was registered at clinicaltrials.gov as NCT03348176.

Indexed as

DietFeeding BehaviorFood PreferencesInfant Nutritional Physiological PhenomenaTasteEnergy IntakeFemaleFruitHumansInfantMaleNetherlandsVegetablescomplementary feedingdietary assessmentfood intakesweet tasteyoung children

Identifiers

PMID40113172
PMCPMC12121417

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.