Evidence map›Paper›PMID 40113087›Full record

ArticleIndian heart journal

Nuclear imaging studies in patients with an indeterminate diagnosis of infective endocarditis: A retrospective analysis of a case series.

Ísis da Capela Pinheiro, Alysson Selton Santiago, Vitor Deriquehem de Araújo Silva, Lucas Ferreira de Oliveira, Rebeca Maria Gomes Guimarães Alves, Ana Glória Bucar, João Mansur Filho, Lúcia Helena Alvares Salis, Nelson Albuquerque de Souza E Silva, Roberto Muniz Ferreira

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Ísis da Capela PinheiroFederal University of Rio de Janeiro, Edson Saad Heart Institute, Rio de Janeiro, RJ, Brazil, Rua Professor Rodolpho Paulo Rocco 255, University city, Rio de Janeiro, RJ, 21941-617, Brazil; Samaritano Hospital, Rio de Janeiro, RJ, Brazil, Rua Bambina 98, Botafogo, Rio de Janeiro, RJ, 22251-050, Brazil.
Alysson Selton SantiagoFederal University of Rio de Janeiro, Edson Saad Heart Institute, Rio de Janeiro, RJ, Brazil, Rua Professor Rodolpho Paulo Rocco 255, University city, Rio de Janeiro, RJ, 21941-617, Brazil.
Vitor Deriquehem de Araújo SilvaFederal University of Rio de Janeiro, Edson Saad Heart Institute, Rio de Janeiro, RJ, Brazil, Rua Professor Rodolpho Paulo Rocco 255, University city, Rio de Janeiro, RJ, 21941-617, Brazil.
Lucas Ferreira de OliveiraFederal University of Rio de Janeiro, Edson Saad Heart Institute, Rio de Janeiro, RJ, Brazil, Rua Professor Rodolpho Paulo Rocco 255, University city, Rio de Janeiro, RJ, 21941-617, Brazil.
Rebeca Maria Gomes Guimarães AlvesFederal University of Rio de Janeiro, Edson Saad Heart Institute, Rio de Janeiro, RJ, Brazil, Rua Professor Rodolpho Paulo Rocco 255, University city, Rio de Janeiro, RJ, 21941-617, Brazil.
Ana Glória BucarFederal University of Rio de Janeiro, Edson Saad Heart Institute, Rio de Janeiro, RJ, Brazil, Rua Professor Rodolpho Paulo Rocco 255, University city, Rio de Janeiro, RJ, 21941-617, Brazil.
João Mansur FilhoSamaritano Hospital, Rio de Janeiro, RJ, Brazil, Rua Bambina 98, Botafogo, Rio de Janeiro, RJ, 22251-050, Brazil.
Lúcia Helena Alvares SalisFederal University of Rio de Janeiro, Edson Saad Heart Institute, Rio de Janeiro, RJ, Brazil, Rua Professor Rodolpho Paulo Rocco 255, University city, Rio de Janeiro, RJ, 21941-617, Brazil.
Nelson Albuquerque de Souza E SilvaFederal University of Rio de Janeiro, Edson Saad Heart Institute, Rio de Janeiro, RJ, Brazil, Rua Professor Rodolpho Paulo Rocco 255, University city, Rio de Janeiro, RJ, 21941-617, Brazil.
Roberto Muniz FerreiraFederal University of Rio de Janeiro, Edson Saad Heart Institute, Rio de Janeiro, RJ, Brazil, Rua Professor Rodolpho Paulo Rocco 255, University city, Rio de Janeiro, RJ, 21941-617, Brazil; Samaritano Hospital, Rio de Janeiro, RJ, Brazil, Rua Bambina 98, Botafogo, Rio de Janeiro, RJ, 22251-050, Brazil. Electronic address: betomf@terra.com.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the role of nuclear imaging (NI) in evaluating inconclusive cases with suspicion of infective endocarditis (IE).

methodsConsecutive patients with an indeterminate diagnosis of IE who underwent labelled leucocyte scintigraphy (LS) or

resultsA total of 85 NI scans (28 FDG-PET/CT, 57 LS) from 76 patients were evaluated, of whom 48 (63.2 %) underwent only LS, 19 (25 %) only FDG-PET/CT, and 9 (11.8 %) both studies. Average age was 63.8 years (SD ± 18.5) and 51.3 % were women. Prosthetic valves were present in 15.8 % of cases, and intracardiac devices in 10.5 %. Among the 76 patients, 18 (23.7 %) had NI findings suggestive of IE. A total of 28 patients (36.8 %) were ultimately diagnosed with IE, 28.6 % of whom had confirmed infections by NI scans. Echocardiographic results had a low level of agreement with NI findings in those diagnosed with IE (kappa = -0.44).

conclusionsNuclear imaging contributed to the diagnosis of IE in approximately 30 % of subsequently confirmed cases, which were initially classified as inconclusive by echocardiography. The low level of agreement between these methods underscores their complementary role in the diagnosis of IE, particularly in indeterminate cases.

Indexed as

EndocarditisPositron Emission Tomography Computed TomographyRadionuclide ImagingAgedEchocardiographyFemaleFluorodeoxyglucose F18HumansMaleMiddle AgedRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18RadiopharmaceuticalsEndocarditisPositron emission tomographyScintigraphy

Identifiers

PMID40113087
PMCPMC12138126

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.