Evidence map›Paper›PMID 40112250›Full record

ArticlePloS one2025

Associations with HIV preexposure prophylaxis use by cisgender female sex workers in two Ugandan cities.

Richard Muhindo, Rachel King, Whitney Irie, Andrew Mujugira, Edith Nakku-Joloba, Stephen Okoboi, Patience Muwanguzi, Eva Laker Odongpiny, Nazarius Mbona Tumwesigye, Barbara Castelnuovo

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Richard MuhindoDepartment of Nursing, Makerere University College of Health Sciences, Kampala, Uganda.ORCID https://orcid.org/0000-0002-3249-117X
Rachel KingUniversity of California, San Francisco, California, United States of America.ORCID https://orcid.org/0000-0002-0085-3498
Whitney IrieBoston College, Chestnut Hill, Massachusetts, United States of America.
Andrew MujugiraInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Edith Nakku-JolobaMakerere University School of Public Health, Kampala, Uganda.
Stephen OkoboiInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Patience MuwanguziDepartment of Nursing, Makerere University College of Health Sciences, Kampala, Uganda.
Eva Laker OdongpinyInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.
Nazarius Mbona TumwesigyeMakerere University School of Public Health, Kampala, Uganda.
Barbara CastelnuovoInfectious Diseases Institute, Makerere University College of Health Sciences, Kampala, Uganda.

Funding

University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health SciencesD43TW010132 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI SEWANKAMBO, NELSON K · 2015 to 2019
$4.3M
FIC NIH HHS D43 TW009343FIC NIH HHS D43 TW010132
6 · The paper itself

Abstract

backgroundSex workers of all genders have a high risk of HIV acquisition and are a priority population for HIV pre-exposure prophylaxis (PrEP). We aimed to assess current oral PrEP use and associated factors among cisgender female sex workers (FSW) in two Ugandan cities.

methodsWe administered a survey questionnaire to 236 HIV-negative FSW in the cities of Mbale and Mbarara from January to March 2020. The survey was nested in a quasi-experimental study to assess the effect of peer education and text message reminders on the uptake of regular sexually transmitted infection (STI) and HIV testing. Using interviewer-administered questionnaires, we obtained data on current self-reported tenofovir-based oral PrEP use. We used modified Poisson regression with robust standard errors to evaluate the factors associated with current oral PrEP usage.

resultsNearly 70% of FSWs reported taking an HIV test during the past three months. Among the respondents, 33% (33/100) in Mbale and 67% (91/136) in Mbarara reported having ever heard of PrEP. However, only 9.7% (23/236) self-reported currently taking oral-PrEP. In Mbarara, FSWs were twice as likely to be aware of or use oral PrEP than those in Mbale (adjusted prevalence ratio [aPR] 2.33; 95% confidence interval (CI) 1.19-3.97; p = 0.01). Additionally, current use was positively associated with attainment of secondary (aPR 2.50; 95% CI: 1.14-5.45; p = 0.02) or tertiary education (aPR 3.12; 95% CI: 1.09-8.96; p = 0.03).

conclusionPrEP use in this cohort of FSWs was low and was associated with location and level of education. To increase PrEP uptake among FSWs, targeted educational campaigns and implementation studies are needed, particularly for those with lower levels of education.

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSex WorkersAdolescentAdultAnti-HIV AgentsCitiesFemaleHealth Knowledge, Attitudes, PracticeHumansSurveys and QuestionnairesTenofovirUgandaYoung AdultAnti-HIV AgentsTenofovir

Identifiers

PMID40112250
PMCPMC11925456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.