ArticleProceedings of the National Academy of Sciences of the United States of America2025
Highly spatial-temporal electrochemical profiling of molecules trafficking at a single mitochondrion in one living cell.
Kang Liu, Lina Wu, Yuanyuan Ma, Desheng Chen, Rujia Liu, Xiaobo Zhang, Dechen Jiang, Rongrong Pan
Abstract read
In one paragraphArticle in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
8 authors.
Kang Liu *The State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center, Nanjing University, Nanjing 210093, Jiangsu, China.
Lina Wu *School of Food Science and Pharmaceutical Engineering, Nanjing Normal University, Nanjing 210023, Jiangsu, China.
Yuanyuan MaThe State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center, Nanjing University, Nanjing 210093, Jiangsu, China.
Desheng ChenThe State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center, Nanjing University, Nanjing 210093, Jiangsu, China.
Rujia LiuSchool of Chemical Sciences, University of Chinese Academy of Science, Beijing 100190, China.
Xiaobo ZhangThe State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center, Nanjing University, Nanjing 210093, Jiangsu, China.ORCID 0000-0003-0222-2515 Dechen JiangThe State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center, Nanjing University, Nanjing 210093, Jiangsu, China.ORCID 0000-0002-2845-3621 Rongrong PanThe State Key Lab of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center, Nanjing University, Nanjing 210093, Jiangsu, China.ORCID 0000-0002-6958-429X Funding
MOST | National Natural Science Foundation of China (NSFC) 22025403MOST | National Natural Science Foundation of China (NSFC) 22374068;22104051Young Elite Scientists Sponsorship Program by CAST 2023QNRC001Young Elite Scientists Sponsorship Program by JSAST TJ-2023-097
6 · The paper itselfAbstract
Simultaneous profiling of multiple molecules trafficking at a single organelle and the surrounding cytosol within a living cell is crucial for elucidating their functions, necessitating advanced techniques that provide high spatial-temporal resolution and molecule specificity. In this study, we present an electrochemical nanodevice based on a θ-nanopipette designed to coanalyze calcium ions (Ca
Indexed as
CalciumElectrochemical TechniquesMitochondriaAutophagyCalcium SignalingCytosolHeLa CellsHumansLysosomesReactive Oxygen SpeciesCalciumReactive Oxygen Specieselectrochemical analysishighly spatial–temporal profilingmolecule traffickingsingle living cellsingle mitochondrion
Identifiers
PMID40112109
PMCPMC11962482
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