ArticleAmerican journal of physiology. Heart and circulatory physiology2025
Parental obesity predisposes male and female offspring to exacerbated cardiac dysfunction and increased mortality after myocardial infarction.
Article in American journal of physiology. Heart and circulatory physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Sex-dependent epigenomic and transcriptomic reprogramming links maternal obesity to cardiac remodeling in adult offspring.American journal of physiology. Heart and circulatory physiology · 2026Article
- Sex differences in the developmental programming of cardiovascular and renal risk across the lifespan.American journal of physiology. Renal physiology · 2026Review
- Parental Obesity and Offspring Risk for Cardiorenal Diseases.Current hypertension reports · 2026Review
- The Metabolic Role of Mitochondria in the Perinatal Cardiac Development and Cardiovascular Diseases.Exploration (Beijing, China) · 2026Review
- Review
- Reply to Skalidis et al.American journal of physiology. Heart and circulatory physiology · 2025Article
- Inherited burdens: the cardiac cost of parental obesity in offspring following myocardial infarction.American journal of physiology. Heart and circulatory physiology · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Acute myocardial infarction (MI) is a leading cause of death worldwide, accounting for >1 million deaths/year in the United States alone. Although parental obesity is a risk factor for offspring cardiovascular diseases, the impact of parental obesity on offspring outcomes after MI is unknown. This study examined if non-obese male and female offspring from obese Sprague-Dawley rat parents fed a high-fat diet (HFD-Offs,
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Registered trials
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