Trial reportJournal of cosmetic dermatology2025
Comparison of the Effects of Adipose Extracellular Matrix/Stromal Vascular Fraction Gel Injection and CO
Trial report in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06116162 (Department of Dermatology of Xijing Hospital of Air Force Medicial University), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Department of Dermatology of Xijing Hospital of Air Force Medicial University
Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Laser, Microneedling, and Combination Therapies for Moderate to Severe Acne Atrophic Scars: A Systematic Review and Network Meta-Analysis.Aesthetic plastic surgery · 2026Pooled it
- Minimally invasive interventions for atrophic acne scars: a PubMed/PMC-based systematic evidence review and exploratory network meta-analysis toward phenotype-guided interpretation.Frontiers in surgery · 2026Pooled it
- Effectiveness of a rhGM-CSF-Containing Gel on Promoting Wound Healing After 1927-nm Fractional Thulium Fiber Laser Treatment of Atrophic Acne Scars: A Prospective, Randomized, Split-Face, and Evaluator-Blinded Clinical Trial.Aesthetic plastic surgery · 2026Trial
- Fractional microneedle radiofrequency for photoaging and atrophic acne scar: a split-face clinical observation of two devices.Lasers in medical science · 2026Trial
- Comparative Effectiveness of Fractional COClinical, cosmetic and investigational dermatology · 2026Article
- Wound Healing: Harnessing Extracellular Vesicles Derived from Adipose-Derived Stem Cells.International journal of nanomedicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundAdipose extracellular matrix/stromal vascular fraction gel (ECM/SVF-gel) contains adipose-derived stem cells, extracellular matrix, and other cell components, and possesses the ability to promote collagen production and serve as a filling agent.
aimTo assess the efficacy and safety of ECM/SVF-gel injection for the treatment of acne scars, compared to CO
methodsWe performed an open-label, investigator-initiated, assessor-blinded, split-face trial in Xijing Hospital, China, between July 11, 2020, and December 30, 2022. Patients exhibiting moderate to severe acne scars were randomly assigned to a single ECM/SVF-gel injection on one half of the face or two sessions of CO
resultsA total of 11 participants were enrolled, and 10 completed the follow-up. The mean age of patients was 27.5 ± 4.2, 7 female and four male, seven with Fitzpatrick skin Type III and four with Type IV. At 24weeks, the mean change in ECCA score was -60.25 on the side of ECM/SVF-gel injection and - 43.25 on the side of CO
conclusionsECM/SVF-gel injection is an effective and safe approach in the treatment of acne scars.
trial registrationClinicalTrials.gov number: NCT06116162.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.