Evidence map›Paper›PMID 40111952›Full record

ArticlePloS one2025

Introduction of "MAPS" wound healing index and its correlation with guided bone regeneration outcome.

Amanda Rodriguez, Diego Velasquez, Leonardo Marquez, Jose Maria Ramos, Nataly Zambrana, Maria Masotti, Oliver Kripfgans, Hsun-Liang Chan

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Amanda RodriguezDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.ORCID 0000-0001-6011-6708
Diego VelasquezPrivate Practice, Fenton, Michigan, United States of America.
Leonardo MarquezSchool of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.
Jose Maria RamosDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.
Nataly ZambranaDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.
Maria MasottiSchool of Public Health, University of Michigan, Ann Arbor, Michigan, United States of America.
Oliver KripfgansDepartment of Radiology Michigan Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
Hsun-Liang ChanDepartment of Periodontics and Oral Medicine, School of Dentistry, University of Michigan, Ann Arbor, Michigan, United States of America.ORCID 0000-0001-5952-0447

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

methodsThe MAPS score was introduced to evaluate the bioMechanical, Aesthetic/Anatomical, Pathophysiologic, and Subject-related parameters for the healing assessment of 20 patients who underwent GBR in the posterior mandible retrospectively. Intraoral photography was taken at 3-, 10-, 21 days, and 5 months, resulting in 80 follow-up visits. Two independent examiners evaluated the photos giving scores for each timepoint and tested against horizontal bone gain (CBCT) for predictability.

resultsCohen's Kappa values showed high intra- and inter-examiner agreement. Pearson's correlation showed an inverse correlation between baseline bone width and bone changes at a 3 mm level (R2 = 0.23). The higher M, A, and P values at any time point were associated with higher bone gain. The 10-day MAPS score turns out the most predictive of bone gain (RMSE 1.32, R2 0.75). In addition, increasing the average P score by 1 point at 10 days is associated with an increase in bone gain of 1.23 (p=.057).

conclusionThe MAPS score improves consistently over the 5-month healing period. However, no statistically significant difference is observed between the scores at 21 days and 5 months, reflecting the clinical healing pattern for GBR. The overall MAPS score correlated with bone changes after GBR procedures, indicating its potential for estimating hard tissue regenerative outcomes.

Indexed as

Bone RegenerationMandibleWound HealingAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcome

Identifiers

PMID40111952
PMCPMC11925305

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