ArticleEJNMMI physics2025
Towards fully automatized [177Lu]Lu-PSMA personalized dosimetry based on 360° CZT whole-body SPECT/CT: a proof-of-concept.
Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- Clinical value of per-treatment whole-body single-time-point automated dosimetry for [European journal of nuclear medicine and molecular imaging · 2026Article
- 3D-ring CZT gamma cameras in theranostics: is it a revolution?EJNMMI reports · 2026Article
- Validation of the collapsed-cone superposition for whole-body patient-specific dosimetry in [177Lu]Lu-PSMA-617 radionuclide therapy.Medical physics · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe advent of 360° CZT gamma-cameras allows to conceive personalised dosimetry studies from whole-body SPECT/CT data. We aimed to demonstrate the proof-of-concept of an automated personalized dosimetry pipeline for [
methodsThe organ segmentation is based on a nnU-Net framework that was trained to allow for the segmentation of 23 organs and structures over all the body. The method implemented to model the energy deposition is the collapsed-cone-superposition (CCS) taking into account non-uniform activity and density distributions. Ten patients with metastatic castration resistant prostate cancer treated [
resultsThe median (IQR) calculation time with SimpleDose (SD), for segmentation, computation of dose-rates and descriptive statistics was 161 (23) seconds at a resolution of 2.46 × 2.46 × 2.46 mm
conclusionThe SimpleDose platform demonstrated its capability to compute organ-absorbed-dose rates in a simple and fast manner with close results to the standard MIRD approach for soft-tissues organs. SimpleDose is freely available for demonstration purpose as a Software as a Service (SaaS) at https://oncometer3d.com .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.