ArticleMethods in molecular biology (Clifton, N.J.)2025
Primary Central Nervous System (CNS) Cultures with Mixed Neural Cell Types to Study Correlative Effects of High Glucocorticoids on Astrocytes, Oligodendrocytes, and Myelination Markers.
Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Transcriptomic Challenges We Faced with Animal Models for Neurological Disorders.Current issues in molecular biology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Dissociated glial and neuronal precursors from the spinal cord or cerebral cortex of late rat embryos are cultured on top of glass coverslips to ascertain the in vitro effects of high glucocorticoid levels on the process of myelination and on astrocyte markers during postnatal development and determine the dependence of those effects on glucocorticoid receptor activation. The study includes the immunohistochemical processing of culture-carrying coverslips with antibodies to astrocytic, neuronal, oligodendroglial, and myelin proteins to determine changes in those markers after glucocorticoid treatment. In addition, we describe oligodendrocyte-astrocyte cultures from neonatal embryos to determine the effects of high glucocorticoids on the morphology of oligodendrocytes in the absence of developing neurons.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.