Evidence map›Paper›PMID 40111541›Full record

ArticleClinical rheumatology2025

The ultrasonographic spectrum of toe dactylitis in psoriatic arthritis: a descriptive analysis.

Garifallia Sakellariou, Nicolò Girolimetto, Ilaria Tinazzi, Marco Canzoni, Georgios Filippou, Alberto Batticciotto, Niccolò Possemato, Pierluigi Macchioni, Orazio De Lucia, Christian Dejaco and 3 more

Abstract read
In one paragraph

Article in Clinical rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Garifallia Sakellariou *Department of Internal Medicine and Therapeutics, Università Di Pavia, Pavia, Italy. filiciasak@gmail.com.ORCID http://orcid.org/0000-0002-1849-5123
Nicolò Girolimetto *UO Interaziendale Medicina Interna Ad Indirizzo Reumatologico AUSL BO-IRCCS AOUBO, Bologna, Italy.ORCID http://orcid.org/0009-0005-6249-1508
Ilaria TinazziUnit of Rheumatology, 'Sacro Cuore' Hospital, Negrar, Italy.ORCID http://orcid.org/0000-0002-5231-4250
Marco CanzoniASL Rome 1 UOSD Reumatologia, Ospedale Nuovo Regina Margherita, 00153, Rome, Italy.ORCID http://orcid.org/0000-0001-5797-4154
Georgios FilippouDepartment of Rheumatology, IRCCS Galeazzi-Sant'Ambrogio Hospital, Milan, Italy.ORCID http://orcid.org/0000-0002-1647-2083
Alberto BatticciottoRheumatology Unit, Internal Medicine Department, ASST Sette Laghi, Ospedale Di Circolo, Fondazione Macchi, Varese, Italy.ORCID http://orcid.org/0000-0003-3140-1264
Niccolò PossematoRheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.ORCID http://orcid.org/0009-0007-2312-4566
Pierluigi MacchioniRheumatology Unit, Azienda Unità Sanitaria Locale-IRCCS Di Reggio Emilia, Reggio Emilia, Italy.ORCID http://orcid.org/0000-0003-3469-2861
Orazio De LuciaUOC Clinica Reumatologica, ASST Centro Traumatologico Ortopedico Gaetano Pini-CTO, Milan, Italy.ORCID http://orcid.org/0000-0003-2304-6661
Christian DejacoDepartment of Rheumatology, Hospital of Bruneck (ASAA-SABES), Teaching Hospital of the Paracelsius Medical University, Bruneck, Italy.ORCID http://orcid.org/0000-0002-0173-0668
Luca IdolazziRheumatology Section, Department of Medicine, University of Verona, Verona, Italy.ORCID http://orcid.org/0000-0002-7254-4686
Carmelo PirriDepartment of Neurosciences, Institute of Human Anatomy, University of Padova, Padua, Italy.ORCID http://orcid.org/0000-0002-0119-6549
Annamaria IagnoccoAcademic Rheumatology Center-DSCB Università Degli Studi Di Torino, AO Mauriziano Di Torino, Turin, Italy.ORCID http://orcid.org/0000-0001-5592-724X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDactylitis is a hallmark of psoriatic arthritis (PsA). While its assessment is clinical, recently musculoskeletal ultrasonography (MSUS) has been applied to its monitoring. However, the evidence on MSUS application for toe dactylitis is limited. The aim of this study is to characterize the ultrasonographic features of toe dactylitis in PsA.

methodPatients with PsA and painful toe dactylitis were retrospectively identified from clinical records. Demographic and clinical variables were analyzed. Ultrasound images of the affected toe, allowing the assessment of grey scale (GS) and power Doppler (PD) were collected, to evaluate tenosynovitis, soft tissue oedema (STO), synovitis of metatarsophalangeal (MTP), proximal and distal interphalangeal (PIP, DIP) joints (all graded 0-3), and peritendonitis (PTI) at the MTP and PIP (graded 0-1). Clinical and ultrasonographic features were analyzed through descriptive statistics.

resultsThe study included 26 patients (30 toes) of which 9 (34.5%) females, with mean (sd) age of 46.8 (11.73). All but one patient had an oligoarticular phenotype. Tenosynovitis was the most frequent lesion, with GS abnormalities in 27/30 toes (90%) and PD in 25/30 (83.3%). STO was common (GS in 28/30 (93.33%) toes and PD in 20/30 (66.66%)). Synovitis was less common (63.33%, 46.66% and 33.33% of MTPs, PIPs and DIPs, respectively), while PTI was uncommon, with no patient presenting with PD.

conclusionsUltrasound showed different elementary lesions in toe dactylitis confirming the complexity of this manifestation also at foot. These findings represent a first step toward the development of further imaging studies assessing toe dactylitis in PsA. Key Points • Tenosynovitis and soft tissue oedema were the most common ultrasonographic elementary lesion in acute toe dactylitis in psoriatic arthritis. • Synovitis was less frequent and peritendonitis was very uncommon. • Musculoskeletal ultrasound confirms the presence of multiple lesions in painful toe dactylitis, confirming the complexity of this manifestation.

Indexed as

Arthritis, PsoriaticSynovitisTenosynovitisToe JointToesAdultEdemaFemaleHumansMaleMetatarsophalangeal JointMiddle AgedRetrospective StudiesUltrasonographyUltrasonography, DopplerDactylitisDisabilityFootImagingPsoriatic arthritisUltrasonography

Identifiers

PMID40111541
PMCPMC12078354

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.