Evidence map›Paper›PMID 40111492›Full record

ArticleEuropean radiology2025

Evaluation of induction chemotherapy response using multiphasic dual-energy CT in nasopharyngeal carcinoma.

Huanhuan Ren, Junhao Huang, Daihong Liu, Yao Huang, Xinying Ren, Jing Zhang, Yong Tan, Hong Yu, Jiahui Zheng, Lin Tang and 2 more

Abstract read
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Article in European radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Huanhuan Ren *Department of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Junhao Huang *Department of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Daihong LiuDepartment of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Yao HuangDepartment of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Xinying RenDepartment of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Jing ZhangDepartment of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Yong TanDepartment of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Hong YuDepartment of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Jiahui ZhengDepartment of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Lin TangDepartment of Radiology, Chongqing University Cancer Hospital, Chongqing, China.
Ying WangRadiation Oncology Center, Chongqing University Cancer Hospital, Chongqing, China. wangy123@cqu.edu.cn.
Jiuquan ZhangDepartment of Radiology, Chongqing University Cancer Hospital, Chongqing, China. zhangjq_radiol@foxmail.com.ORCID http://orcid.org/0000-0003-0239-6988

Funding

Chongqing Medical Research Project of Combination of Science and Medicine No. 2024MSXM036Chongqing Science and Health Joint Medical Research Project No.2024ZDXM032Chongqing Shapingba District Technology Innovation and Application Development Project No. 2024108Chongqing Shapingba District Technology Innovation and Application Development Project No. 2024163Chongqing Talent Program No. cstc2021ycjh-bgzxm0023National Natural Science Foundation of China No. 82071883National Natural Science Foundation of China No. 82371937Natural Science Foundation of Chongqing Municipality CSTB2024NSCQ-MSX0899
6 · The paper itself

Abstract

objectivesTo develop a nomogram that assists in selecting nasopharyngeal carcinoma (NPC) patients suitable for induction chemotherapy. MATERIALS AND

methodsThis retrospective study included NPC patients who underwent multiphasic contrast‑enhanced DECT (comprising non-contrast, arterial, and venous phase scanning) between May 2019 and December 2023. The relationships between quantitative DECT-derived parameters and treatment response to induction chemotherapy were analyzed using logistic regression analysis. The predictive performance of a nomogram integrating key predictors was assessed using the area under the receiver operating characteristic curve (AUC).

resultsA total of 294 patients (median age, 53 years; interquartile range, 46-59 years; 224 men) were included. Among these, 215 were responders and 79 were non-responders. The normalized iodine concentration in the arterial phase (nIC

conclusionsWe developed a comprehensive nomogram to predict treatment response to induction chemotherapy by integrating nIC KEY POINTS: Question To date, no reliable method has been established to predict the efficacy of induction chemotherapy for nasopharyngeal carcinoma prior to treatment. Findings nIC

Indexed as

Induction ChemotherapyNasopharyngeal CarcinomaNasopharyngeal NeoplasmsTomography, X-Ray ComputedContrast MediaFemaleHumansMaleMiddle AgedNomogramsRetrospective StudiesTreatment OutcomeContrast MediaInduction chemotherapyNasopharyngeal carcinomaTomography (X-ray computed)Treatment outcome

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.